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Dr Vicky Green

Dr Vicky Green

Post-doctoral Research Scientist

Faculty and Department

  • Faculty of Health Sciences
  • Hull York Medical School

Qualifications

  • PhD (University of Hull)

Summary

Victoria Green obtained a first class honours degree in Biochemistry from the University of York in 1993 before undertaking a PhD at the University of Hull, Department of Medicine looking at "The role of oestrogen and its regulation in pituitary adenomas" which she completed in 1997. Victoria has worked ever since in the Biomedical Sciences Department under its various guises at the University of Hull as a post-doctoral researcher.

Recent outputs

View more outputs

Journal Article

Isolation and characterisation of graves' disease-specific extracellular vesicles from tissue maintained on a bespoke microfluidic device

Foster, H., Wade, M., England, J., Greenman, J., & Green, V. (2021). Isolation and characterisation of graves’ disease-specific extracellular vesicles from tissue maintained on a bespoke microfluidic device. Organs-on-a-Chip, 3, Article 100011. https://doi.org/10.1016/j.ooc.2021.100011

Identification of soluble tissue-derived biomarkers from human thyroid tissue explants maintained on a microfluidic device

Riley, A., Jones, H., England, J., Kuvshinov, D., Green, V., & Greenman, J. (2021). Identification of soluble tissue-derived biomarkers from human thyroid tissue explants maintained on a microfluidic device. Oncology Letters, 22(5), Article 780. https://doi.org/10.3892/ol.2021.13041

Current understanding of nonsurgical interventions for refractory differentiated thyroid cancer: a systematic review

Jones, H., Green, V., England, J., & Greenman, J. (2021). Current understanding of nonsurgical interventions for refractory differentiated thyroid cancer: a systematic review. Future Science OA, 7(7), https://doi.org/10.2144/fsoa-2021-0041

The Changing Face of in vitro Culture Models for Thyroid Cancer Research: A Systematic Literature Review

Chew, D., Green, V., Riley, A., England, R. J., & Greenman, J. (2020). The Changing Face of in vitro Culture Models for Thyroid Cancer Research: A Systematic Literature Review. Frontiers in Surgery, 7, Article 43. https://doi.org/10.3389/fsurg.2020.00043

The effect of radioiodine treatment on the diseased thyroid gland

Riley, A. S., McKenzie, G. A. G., Green, V., Schettino, G., England, R. J. A., & Greenman, J. (2019). The effect of radioiodine treatment on the diseased thyroid gland. International Journal of Radiation Biology, 95(12), 1718-1727. https://doi.org/10.1080/09553002.2019.1665206

Research interests

Tumour Biology

Microfluidics

Extracellular vesicles

Lead investigator

Project

Funder

Grant

Started

Status

Project

Exploiting microfluidic technology to predict chemoradiation responses in HNSCC

Funder

Royal College of Surgeons of Edinburgh

Grant

£10,000.00

Started

31 May 2022

Status

Ongoing

Project

Identification of exosomal miRNA biomarkers in thyroid disease using microfluidics

Funder

British Association of Endocrine & Thyroid Surgeons

Grant

£5,000.00

Started

3 January 2022

Status

Ongoing

Project

Monitoring the secretome of advanced thyroid cancers for metastatic markers

Funder

British Association of Endocrine & Thyroid Surgeons

Grant

£4,993.00

Started

20 May 2019

Status

Complete

Project

Evaluating EV as a therapeutic target in Graves’ disease

Funder

Get A-Head Charitable Trust

Grant

£15,000.00

Started

1 February 2019

Status

Complete

Co-investigator

Project

Funder

Grant

Started

Status

Project

Utilising tissue-on-a-chip technology as an ex vivo model of breast cancer metastatic colonisation

Funder

NC3Rs NC3Rs

Grant

£8,771.00

Started

1 July 2019

Status

Complete

Project

Global analysis of molecular changes in head and neck squamous cell carcinoma (HNSCC) tissue maintained and treated on microfluidic devices

Funder

MRC Medical Research Council

Grant

£44,480.00

Started

1 February 2020

Status

Complete

Project

Development of a multipurpose small animal phantom for pre-clinical radiotherapy studies

Funder

Innovate UK

Grant

£193,197.00

Started

1 April 2016

Status

Complete

Project

In vitro analysis of thyroid cancer and it's response to radiotherapy

Funder

Donate for Research Initiative

Grant

£2,500.00

Started

22 May 2015

Status

Complete

Project

Identification of exosomal miRNA biomarkers in thyroid disease using microfluidics

Funder

ENT UK

Grant

£750.00

Started

1 September 2021

Status

Complete

Postgraduate supervision

I welcome applications from both medically trained individuals and basic scientists to further research into the use of microfluidic devices as a platform for investigating human tissue responses to treatment. In addition I am particularly interested in tumour biology and the role of exosomes in disease and their use as biomarkers

Supervision record

PhD

Primary Supervisor

Samantha Drennan, 2013, (PhD) “Phenotypic and functional characterisation of regulatory T cells in head and neck squamous cell carcinoma”

Joanne Smith, 2016, (PhD) “The Effect of HNSCC-derived Soluble Factors on the Proliferation and Function of Immune Cells”

Second Supervisor

Hannah Beattie, Current (PhD) “Detection of novel biomarkers for identifying thyroid tumours using novel microfluidic technology”

James Dory, Current (PhD) “Investigating the effect of novel bispecifics targeting immunostimulatory molecules to target human tumour tissue using Hull's tissue-on-chip ex vivo platform”

Andrew Riley, 2020 (PhD) “An ex vivo thyroid-on-chip model for the elucidation of drug response and biomarker analysis”

Ruth Bower, 2018 (PhD) “A tumour-on-a-chip system for investigation of radiation based treatment in primary head and neck cancer: a personalised approach”

Elizabeth Roberts, 2018 (PhD) “Generation of an Immunosuppressive Microenvironment by Soluble Factors in Head and Neck Squamous Cell Carcinoma”

Ramsah Cheah, 2016 (PhD) “Monitoring the response of head and neck tumour tissue to irradiation using a microfluidic-based approach

MD

Primary Supervisor

Thomas Haigh, Current (MD) “Using microfluidic technology as a platform to identify exosomal biomarkers of thyroid disease”

Second Supervisor

Rishi Srivastava, 2017 (MD) “Radiation Response of Head and Neck Squamous Cell Carcinoma Using Early Markers of Apoptosis and Proliferation, Utilising a Microfluidic Approach”

Tosief Zahoor, 2016 (MD) “Does HPV-16 seropositivity correlate with T-cell distribution providing additional prognostic information in infected HNSCC patients?

Simon Carr, 2013 (MD) “Analysis of radiation-induced cell death in head and neck squamous cell carcinoma and rat liver maintained in microfluidic device”

Deborah Sylvester (2012 (MD) “Development of microfluidic based devices for studying tumour biology and evaluating treatment response in head and neck cancer biopsies”

MSc

Primary Supervisor

Jordan Lee Greaves, Current (MSc) “Exploiting microfluidic technology to predict chemoradiation responses in HNSCC”

Przemek Golebiewski, Current (MSc) “Development of bespoke microfluidic technology to identify thyroid tumour biomarkers”

Hayley Foster, 2022, (MSc) “Evaluating EV as a therapeutic target in Graves’ disease”

Second Supervisor

Jake Owen, Current (MSc) “Bioinformatic analysis of the effects of bispecifics on HNSCC tissue maintained on a microfluidic device”

Gordon McKensie, 2019 (MSc) “The effects of corticosteroids on immune modulating factors from Graves’ disease tissue maintained in a microfluidic device”

Beth Broughton, 2018 (MSc) “Characterisation of Intratumoral Immune Cells and Cytokines in Thyroid Cancer”

Chee Ching Chan, 2014 (MSc) “Analysis of Head and Neck Squamous Cell Carcinoma Tissue Maintained in a Micro fluidic Device Following Chemotherapy”

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