Journal Article
Microplastics in human blood: Polymer types, concentrations and characterisation using μFTIR
Leonard, S. V. L., Liddle, C. R., Atherall, C. A., Chapman, E., Watkins, M., Calaminus, S. D. J., & Rotchell, J. M. (2024). Microplastics in human blood: Polymer types, concentrations and characterisation using μFTIR. Environment International, 188, Article 108751. https://doi.org/10.1016/j.envint.2024.108751
Quantum Dot Imaging Agents: Haematopoietic Cell Interactions and Biocompatibility
Naylor-Adamson, L., Price, T. W., Booth, Z., Stasiuk, G. J., & Calaminus, S. D. (2024). Quantum Dot Imaging Agents: Haematopoietic Cell Interactions and Biocompatibility. Cells, 13(4), Article 354. https://doi.org/10.3390/cells13040354
Impact of Surface Ligand on the Biocompatibility of InP/ZnS Quantum Dots with Platelets
Gil, H. M., Booth, Z., Price, T. W., Lee, J., Naylor‐Adamson, L., Avery, M., …Stasiuk, G. J. (in press). Impact of Surface Ligand on the Biocompatibility of InP/ZnS Quantum Dots with Platelets. Small, Article 2304881. https://doi.org/10.1002/smll.202304881
Platelet zinc status regulates prostaglandin-induced signaling, altering thrombus formation
Coupland, C. A., Naylor-Adamson, L., Booth, Z., Price, T. W., Gil, H. M., Firth, G., …Calaminus, S. D. (2023). Platelet zinc status regulates prostaglandin-induced signaling, altering thrombus formation. Journal of thrombosis and haemostasis : JTH, 21(9), 2545-2558. https://doi.org/10.1016/j.jtha.2023.05.008
Should aspirin be replaced with ADP blockers or anti-GPVI to manage thrombosis?
Khan, H., Ghulam, T., Ahmed, N., Babar, M. R., Calaminus, S. D., & Yusuf, M. Z. (2022). Should aspirin be replaced with ADP blockers or anti-GPVI to manage thrombosis?. Vascular Biology, https://doi.org/10.1530/vb-22-0010
Research interests
The Calaminus lab investigates how platelets respond and activate to a range of different agonists and inhibitors to fully understand the range of functions that platelet complete within the body. To do this we use a range of assays: platelet spreading, in vitro thrombus formation, FACs analysis, western blotting and platelet aggregation.
We aim to not only understand how platelet respond to natural environments, but also how addition of external pollutants such as microplastics then affect and disturb these environments leading to platelet dysfunction.
Lead investigator
Project
Funder
Grant
Started
Status
Project
Effect of hypoxia on prostacyclin-mediated inhibition of platelet function
Funder
British Heart Foundation
Grant
£110,353.00
Started
1 January 2023
Status
Ongoing
Project
Is zinc a critical modulator of cyclic nucleotide signalling?
Funder
British Heart Foundation
Grant
£108,740.00
Started
1 October 2019
Status
Complete
Project
Platelet cAMP signalling controls thrombosis through enhanced embolisation
Funder
British Heart Foundation
Grant
£106,467.00
Started
1 October 2015
Status
Complete
Co-investigator
Project
Funder
Grant
Started
Status
Project
TARGETING THE MYOSIN LIGHT CHAIN PHOSPHATASE WITH PEPTIDE DISRUPTORS: A NOVEL ANTIPLATELET THERAPEUTIC APPROACH
Funder
British Heart Foundation
Grant
£110,680.00
Started
3 July 2023
Status
Ongoing
Project
ThrombiGlow: ‘Smart’ Multimodal Platelet Specific ‘Theranostic’ Drug Delivery Imaging
Funder
British Heart Foundation
Grant
£107,146.00
Started
1 February 2017
Status
Complete
Postgraduate supervision
Platelet Biology
If self funded students wish to approach me to investigate the possibility of completing a PhD, then please email me directly using simon.calaminus@hyms.ac.uk