I contribute to various aspects of the Hull York Medical School MBBS (lectures, biopracticals, scholarship and special interest programme), to the BSc Biomedical Sciences (lectures, projects) and to the MSc in Pharmacology and Drug Development and the MSc Biomedical Sciences.
I'm also the postgreaduate training academic lead of HYMS.
Journal Article
α-Synuclein Deletion Impairs Platelet Function: A Role for SNARE Complex Assembly
Sennett, C., Jia, W., Khalil, J. S., Hindle, M. S., Coupland, C., Calaminus, S. D., Langer, J. D., Frost, S., Naseem, K. M., Rivero, F., Ninkina, N., Buchman, V., & Aburima, A. (2024). α-Synuclein Deletion Impairs Platelet Function: A Role for SNARE Complex Assembly. Cells, 13(24), Article 2089. https://doi.org/10.3390/cells13242089
Complex Transcriptional Profiles of the PPP1R12A Gene in Cells of the Circulatory System as Revealed by In Silico Analysis and Reverse Transcription PCR
Saldanha, P. A., Bolanle, I. O., Palmer, T. M., Nikitenko, L. L., & Rivero, F. (2022). Complex Transcriptional Profiles of the PPP1R12A Gene in Cells of the Circulatory System as Revealed by In Silico Analysis and Reverse Transcription PCR. Cells, 11(15), Article 2315. https://doi.org/10.3390/cells11152315
Bruton's tyrosine kinase inhibitors impair FcγRIIA-driven platelet responses to bacteria in chronic lymphocytic leukemia
Naylor-Adamson, L., Chacko, A., Booth, Z., Caserta, S., Jarvis, J., Khan, S., Hart, S. P., Rivero, F., Allsup, D. J., & Arman, M. (2021). Bruton’s tyrosine kinase inhibitors impair FcγRIIA-driven platelet responses to bacteria in chronic lymphocytic leukemia. Frontiers in immunology, 12, Article 766272. https://doi.org/10.3389/fimmu.2021.766272
Interactome and evolutionary conservation of dictyostelid small GTPases and their direct regulators
Forbes, G., Schilde, C., Lawal, H., Kin, K., Du, Q., Chen, Z.-H., Rivero, F., & Schaap, P. (in press). Interactome and evolutionary conservation of dictyostelid small GTPases and their direct regulators. Small GTPases, https://doi.org/10.1080/21541248.2021.1984829
Research interests
Dr Rivero's lab specialises in research into the cytoskeleton, a key player in almost all cellular processes, including motility, cytokinesis, cell-to-cell and cell-susbstrate interactions and intracellular transport. Dr. Rivero is currently pursuing lines of research that explore aspects of the actin cytoskeleton and the signalling pathways that regulate its remodelling in blood platelets. Platelet activation is the result of multiple exquisitely integrated signalling cascades that drive the morphological changes required for adhesion, spreading, aggregation and secretion at the sites of vascular damage. Those signalling pathways ultimately drive remodelling of the platelet cytoskeleton. Platelet physiology is of particular medical relevance because of the role of thrombosis in common cardiovascular conditions such as heart attack and stroke.
The ultimate goals of Dr Rivero's research are a better understanding of platelet function (basic science aspect) and the development of improved diagnostic/therapeutical strategies for the management of states of platelet hyperactivation and other conditions involving platelet/endothelial cell function (translational aspect).
Lead investigator
Project
Funder
Grant
Started
Status
Project
TARGETING THE MYOSIN LIGHT CHAIN PHOSPHATASE WITH PEPTIDE DISRUPTORS: A NOVEL ANTIPLATELET THERAPEUTIC APPROACH
Funder
British Heart Foundation
Grant
£110,680.00
Started
3 July 2023
Status
Ongoing
Project
The impact of heat waves on gene expression at early development stages across eukaryotic scales: insights from social amoeba and zebrafish.
Funder
Natural Environment Research Council
Grant
£20,602.00
Started
1 November 2024
Status
Ongoing
Project
Coronin is a negative regulator of platelet spreading and thrombus formation
Funder
British Heart Foundation
Grant
£106,915.00
Started
1 July 2016
Status
Complete
Co-investigator
Project
Funder
Grant
Started
Status
Project
Wolfson Equipment bid 2023 - Confocal Imaging ZEISS Elyra 7 with Lattice SIM²
Funder
Wolfson Foundation
Grant
£500,000.00
Started
1 October 2024
Status
Ongoing
Postgraduate supervision
Platelet Biology, Cell Signalling, Cytoskeleton