Summary
Professor Morice is Head of Respiratory Medicine at HYMS, based at the University of Hull. He is also an Honorary Consultant Physician at Hull & East Yorkshire Hospitals NHS Trust. Professor Morice specialises in the diagnosis and treatment of cough, and runs the Hull Cough Clinic. He also runs the Hull Respiratory Clinical Trials Unit, specialising in the treatment of asthma and COPD.
The Hull Cough Clinic is one of the largest centres within Europe, with an international pattern of referral. Unique investigational strategies provide diagnosis and treatment advances, which are incorporated into national and international guideline documents.
Professor Morice has led the European Respiratory Society and British Thoracic Society Taskforces on Cough.
Journal Article
Use of the oral beta blocker bisoprolol to reduce the rate of exacerbation in people with chronic obstructive pulmonary disease (COPD): a randomised controlled trial (BICS)
Cotton, S., Devereux, G., Abbas, H., Briggs, A., Campbell, K., Chaudhuri, R., …Lipworth, B. J. (2022). Use of the oral beta blocker bisoprolol to reduce the rate of exacerbation in people with chronic obstructive pulmonary disease (COPD): a randomised controlled trial (BICS). Trials, 23(1), Article 307. https://doi.org/10.1186/s13063-022-06226-8
Eliapixant (BAY 1817080), a P2X3 receptor antagonist, in refractory chronic cough: a randomised, placebo-controlled, crossover phase 2a study
Morice, A., Smith, J. A., McGarvey, L., Birring, S. S., Parker, S. M., Turner, A., …Friedrich, C. (2021). Eliapixant (BAY 1817080), a P2X3 receptor antagonist, in refractory chronic cough: a randomised, placebo-controlled, crossover phase 2a study. European respiratory journal, 58(5), Article 2004240. https://doi.org/10.1183/13993003.04240-2020
Research interests
Professor Morice specialises in the diagnosis and treatment of cough, and runs the Hull Cough Clinic. He also runs the Hull Respiratory Clinical Trials Unit, specialising in the treatment of asthma and COPD.
The Hull Cough Clinic is one of the largest centres within Europe, with an international pattern of referral. Unique investigational strategies provide diagnosis and treatment advances, which are incorporated into national and international guideline documents.
Professor Morice has led the European Respiratory Society and British Thoracic Society Taskforces on Cough.
Project
Funder
Grant
Started
Status
Project
AX-8 Clinical Research Collaboration
Funder
Hull University Teaching Hospitals NHS Trust
Grant
£21,285.00
Started
1 June 2016
Status
Complete
Project
VOLCANO-2: A double-blind, placebo controlled study of the efficacy and safety of three doses of Orvepitant in subjects with chronic refractory cough
Funder
Hull University Teaching Hospitals NHS Trust
Grant
£42,493.00
Started
1 August 2017
Status
Complete
Project
Lavolta - A phase III, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of
Funder
Hull University Teaching Hospitals NHS Trust
Grant
£19,047.00
Started
18 May 2014
Status
Complete
Project
OSPREY: An Observational Study of the Phenotype and pRescribing in East Yorkshire and its relevance to the introduction of new prescribing guidelines for airways disease.
Funder
AstraZeneca UK Limited
Grant
£163,413.00
Started
1 October 2016
Status
Complete
Project
Orbit-4: A multi-centre, randomised, double-blind, placebo-controlled study to evaluate the safety and efficacy of Pulmaquin in the management of chronic lung infections with pseudomonas aeruginosa in subjects with non-cystic fibrosis bronchiectasis, including 28
Funder
Aradigm Corporation
Grant
£30,144.00
Started
31 October 2014
Status
Complete
Project
TUF: The Utility of FeNo in the differential diagnosis of chronic cough
Funder
Aerocrine AB
Grant
£30,000.00
Started
2 November 2015
Status
Complete
Project
Development Costs: A Study to Assess the Effect of AF-219 on Cough Reflex Sensitivity in Both Healthy and Chronic Cough Subjects
Funder
Afferent Pharmaceuticals Inc
Grant
£62,207.00
Started
5 October 2015
Status
Complete
Project
AFFERENT14: A Study to Assess the Effect of AF-219 on Cough Reflex Sensitivity in Both Healthy and Chronic Cough Subjects
Funder
Afferent Pharmaceuticals Inc
Grant
£140,667.00
Started
5 October 2015
Status
Complete
Project
AFFERENT12: AF219-012: A 12 week Study to assess the Efficacy and tolerability of AF 219 in subjects with treatm
Funder
Afferent Pharmaceuticals Inc
Grant
£22,020.00
Started
1 March 2016
Status
Complete
Project
Proof of Concept study (POC) to investigate the effect of ambroxol hydrochloride (20mg lozenges) on the cough reflex in patients with acute upper respiratory tract infection
Funder
Sanofi Aventis
Grant
£27,342.00
Started
1 October 2017
Status
Complete
Project
TUSSIX: MTI-110 - A randomized, double-blind, placebo-controlled study of the efficacy, safety, and tolerability of Serlopitant for the treatment of refractory chronic cough
Funder
Hull University Teaching Hospitals NHS Trust
Grant
£16,546.00
Started
1 December 2017
Status
Complete