Dr Ahmed Aburima

Dr Ahmed Aburima

Lecturer in Cardiovascular Science

Faculty and Department

  • Faculty of Health Sciences
  • Hull York Medical School

Qualifications

  • BSc
  • MSc (University of Bradford)
  • PhD / DPhil (Hull York Medical School)
  • PGCert (University of Hull)

Recent outputs

View more outputs

Journal Article

Thrombospondin-1 promotes hemostasis through modulation of cAMP signaling in blood platelets

Aburima, A., Berger, M., Spurgeon, B. E., Webb, B. A., Wraith, K. S., Febbraio, M., …Naseem, K. M. (2021). Thrombospondin-1 promotes hemostasis through modulation of cAMP signaling in blood platelets. Blood, 137(5), 678-689. https://doi.org/10.1182/blood.2020005382

Effect of induced hypoglycemia on inflammation and oxidative stress in type 2 diabetes and control subjects

Kahal, H., Halama, A., Aburima, A., Bhagwat, A. M., Butler, A. E., Grauman, J., …Atkin, S. L. (2020). Effect of induced hypoglycemia on inflammation and oxidative stress in type 2 diabetes and control subjects. Scientific reports, 10(1), Article 4750. https://doi.org/10.1038/s41598-020-61531-z

Atherogenic lipid stress induces platelet hyperactivity through CD36-mediated hyposensitivity to prostacyclin-; the role of phosphodiesterase 3A.

Berger, M., Raslan, Z., Aburima, A., Magwenzi, S., Wraith, K. S., Spurgeon, B. E., …Naseem, K. M. (2020). Atherogenic lipid stress induces platelet hyperactivity through CD36-mediated hyposensitivity to prostacyclin-; the role of phosphodiesterase 3A. Haematologica, 105(3), 808-819. https://doi.org/10.3324/haematol.2018.213348

Alterations in platelet alpha granule secretion and adhesion on collagen under flow in mice lacking the atypical Rho GTPase RhoBTB3

Berger, M., Riley, D. R. J., Lutz, J., Khalil, J. S., Aburima, A., Naseem, K. M., & Rivero, F. (2019). Alterations in platelet alpha granule secretion and adhesion on collagen under flow in mice lacking the atypical Rho GTPase RhoBTB3. Cells, 8(2), 149. https://doi.org/10.3390/cells8020149

Dyslipidemia-associated atherogenic oxidized lipids induce platelet hyperactivity through phospholipase Cγ2-dependent reactive oxygen species generation

Berger, M., Wraith, K., Woodward, C., Aburima, A., Raslan, Z., Hindle, M. S., …Naseem, K. M. (2019). Dyslipidemia-associated atherogenic oxidized lipids induce platelet hyperactivity through phospholipase Cγ2-dependent reactive oxygen species generation. Platelets, 30(4), 467-472. https://doi.org/10.1080/09537104.2018.1466386

Research interests

Haemostasis and thrombosis

Platelet biology

Innate immunity

Adaptive immunity

Lead investigator

Project

Funder

Grant

Started

Status

Project

PD-L1 promotes platelet activation and enhances thrombus formation.

Funder

British Heart Foundation

Grant

£110,207.00

Started

1 October 2022

Status

Ongoing

Project

α-synuclein is a key novel regulator of platelet function.

Funder

British Heart Foundation

Grant

£108,238.00

Started

1 January 2020

Status

Complete

Postgraduate supervision

The role of platelets in shaping the innate and adaptive immune response.

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