Summary
Dr Shang-Zhong (Sam) Xu is a reader in the Centre for Cardiovascular and Metabolic Research. He obtained his BM in clinical medicine from Shandong Medical University (1986), MSc in Pharmacology from Shanghai Medical University (1989, Shanghai) and MD in Cardiology (1996, Shanghai). He worked as a resident physician, specialist and then associate professor and consultant cardiologist (1989-1998). He was enthusiastic for medical research and moved to Leeds for PhD study (PhD, 2001, Leeds) and then postdoctoral research fellow (2001-2005, Leeds). Sam joined the Postgraduate Medical Institute and Hull York Medical School as a Lecturer in 2005 and became Senior Lecturer, and then Reader in Hull York Medical School. His research focused on ion channels, drug discovery and new target identification for cardiovascular diseases and diabetic complications.
Journal Article
Ca2+ Influx through TRPC Channels Is Regulated by Homocysteine–Copper Complexes
Chen, G., Zeng, B., Jiang, H., Daskoulidou, N., Saurabh, R., Chitando, R. J., & Xu, S. (2023). Ca2+ Influx through TRPC Channels Is Regulated by Homocysteine–Copper Complexes. Biomolecules, 13(6), Article 952. https://doi.org/10.3390/biom13060952
Assessment of mitochondrial dysfunction and implications in cardiovascular disorders
Li, Y., Ma, Y., Dang, Q. Y., Fan, X. R., Han, C. T., Xu, S. Z., & Li, P. Y. (2022). Assessment of mitochondrial dysfunction and implications in cardiovascular disorders. Life Sciences, 306, Article 120834. https://doi.org/10.1016/j.lfs.2022.120834
Recent advances in drug discovery for diabetic kidney disease
Danta, C. C., Boa, A. N., Bhandari, S., Sathyapalan, T., & Xu, S. Z. (2021). Recent advances in drug discovery for diabetic kidney disease. Expert Opinion on Drug Discovery, 16(4), 447-461. https://doi.org/10.1080/17460441.2021.1832077