Leigh came to the University of Hull to study Applied Biology in 1991. He specialised in biotechnology in the final year of his degree and then proceeded to continue into a research career starting with PhD and postdoctoral positions fully funded through industry (Monsanto Inc, USA). Following this he switched fields into medical research in 2000 and has been at Hull ever since. Leigh is an author on over 100 peer-reviewed papers which have been cited over 3500 times (h-index 36), covering a wide range of interests and has worked closely with clinical leads, colleagues in HYMS, Chemistry and Sport Health and Exercise Science as well as commercial partners from City Healthcare Partnership, North of England Medical Hyperbaric Services, Mimir Marine and QinetiQ.
Leigh has helped supervise many students across a wide range of research fields including cancer associated coagulation, diabetes, polycystic ovary syndrome, bioimprinting, tissue engineering, decompression sickness, exercise in clinical populations to clinical trials of investigative medicinal products (CTIMPs) and App development.
Early Human Pathophysiological Responses to Exertional Hypobaric Decompression Stress
Connolly, D., Madden, L., Edwards, V., D'Oyly, T., Harridge, S., Smith, T., & Lee, V. (2023). Early Human Pathophysiological Responses to Exertional Hypobaric Decompression Stress. Aerospace Medicine and Human Performance, 94(10), 738-749. https://doi.org/10.3357/AMHP.6247.2023
Coagulation Profiles in Humans Exposed to Exertional Hypobaric Decompression Stress Determined by Calibrated Automated Thrombogram
Madden, L. A., Vince, R. V., Edwards, V. C., Lee, V. M., & Connolly, D. M. (2023). Coagulation Profiles in Humans Exposed to Exertional Hypobaric Decompression Stress Determined by Calibrated Automated Thrombogram. Hemato, 4(4), 301-310. https://doi.org/10.3390/hemato4040024
Leigh’s main research interest lies within the field of extracellular vesicles in which he has been actively conducting and publishing research since 2003 when he was part of the first ever study investigating the role of extracellular vesicles in decompression sickness. Always keen to contribute to new research Leigh has collaborated across a wide spectrum of projects within the medical field.
Assessing the health economics of two home-based exercise programmes in obese adults
NHS East Riding of Yorkshire Clinical Commissioning Group
1 June 2018
Extracellular vesicles – clinical and/or laboratory based
Cancer associated hypercoagulability – clinical and/or laboratory based
Bioimprinting – laboratory based
Tissue engineering – laboratory based
Diabetes, Obesity and Polycystic ovary syndrome – clinical and/or laboratory based