- BSc (University of Manchester)
- PhD (University of Glasgow)
Tim is Professor of Cardiovascular Biology and Head of the Centre for Atherothrombosis and Metabolic Disease at Hull York Medical School.
Tim obtained an Honours degree in Biochemistry at the University of Manchester and a PhD in Molecular Pharmacology at the University of Glasgow. He carried out postdoctoral training as an American Heart Association Research Fellow in the Cardiology Division at Duke University Medical Centre, North Carolina, USA.
He returned to the UK in 1997 as a Lecturer in Biochemistry at the University of Glasgow and developed an externally funded research programme focusing on cardiovascular cell signalling and disease.
From 2015 he was Professor of Pharmacology and Head of Pharmacology and Experimental Therapeutics at the School of Pharmacy and Medical Sciences at the University of Bradford before taking up his position in Hull in 2018.
Detection of microplastics in human saphenous vein tissue using ?FTIR: a pilot study
Rotchell, J., Jenner, L., Chapman, E., Bennett, R., Bolanle, I., Loubani, M., …Palmer, T. (2023). Detection of microplastics in human saphenous vein tissue using ?FTIR: a pilot study. PLoS ONE, 18(2), Article e0280594. https://doi.org/10.1371/journal.pone.0280594
Complex Transcriptional Profiles of the PPP1R12A Gene in Cells of the Circulatory System as Revealed by In Silico Analysis and Reverse Transcription PCR
Saldanha, P. A., Bolanle, I. O., Palmer, T. M., Nikitenko, L. L., & Rivero, F. (2022). Complex Transcriptional Profiles of the PPP1R12A Gene in Cells of the Circulatory System as Revealed by In Silico Analysis and Reverse Transcription PCR. Cells, 11(15), Article 2315. https://doi.org/10.3390/cells11152315
Revascularisation of type 2 diabetics with coronary artery disease: Insights and therapeutic targeting of O-GlcNAcylation
Bolanle, I. O., Riches-Suman, K., Loubani, M., Williamson, R., & Palmer, T. M. (2021). Revascularisation of type 2 diabetics with coronary artery disease: Insights and therapeutic targeting of O-GlcNAcylation. Nutrition, metabolism, and cardiovascular diseases : NMCD, https://doi.org/10.1016/j.numecd.2021.01.017
Professor Palmer’s interests are identifying the molecular mechanisms responsible for cardiovascular disease. Localised inflammation of branch points within large blood vessels is a pivotal event in the development of atherosclerotic plaque responsible for hear attack and stroke. Inflammation is driven by long-term exposure to chemical signals termed "cytokines" which trigger multiple pathways that ultimately lead to the defective vascular cell function responsible for cardiovascular disease. These processes are also responsible for the failure of bypass and stenting procedures used for acute treatment of patients who have suffered a heart attack.
SOCS VASC - Stabilising suppressor of cytokine signalling 3 (SOCS3) to limit vascular re-modelling in vein graft failure and in-stent restenosis
Hull & East Riding Cardiac Trust Fund
1 December 2019
Enquiries from prospective students welcome. 16 students successfully supervised to completion.
1. Defining mechanisms linking anti-inflammatory signalling with protection of the vasculature from mechanical stress.
2. Identification of novel glucose-dependent alterations responsible for platelet dysfunction in Type 2 diabetes.
3. Defining the molecular basis for re-purposing anti-hyperglycaemic drugs to manage thrombosis in myeloproliferative neoplasm patients.