Professor Steve Archibald

Professor Steve Archibald

Professor in Molecular Imaging

Faculty and Department

  • Faculty of Health Sciences
  • Department of Biomedical Sciences

Summary

Research areas in the Archibald group are PET probe development, chemokine receptor imaging and lab-on-a-chip/ microfluidic devices for radiosynthesis and quality control.

Prof Archibald was awarded a first class BSc degree in Chemistry, Life Systems and Pharmaceuticals by the University of York in 1992 and a PhD in Chemistry by the University of Edinburgh in 1995.

He carried out postdoctoral research at the Universities of Paris-Sud (France), Kansas (USA) and York (UK), before being appointed as a lecturer at the University of Hull in 2000.

Prof Archibald was promoted to Senior Lecturer in 2008, Reader in 2011, Director of the Positron Emission Tomography Research Centre in 2013 and Professor in 2014.

Recent outputs

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Journal Article

The aluminium-[18F]fluoride revolution: simple radiochemistry with a big impact for radiolabelled biomolecules

Archibald, S. J., & Allott, L. (2021). The aluminium-[18F]fluoride revolution: simple radiochemistry with a big impact for radiolabelled biomolecules. EJNMMI Radiopharmacy and Chemistry, 6(1), https://doi.org/10.1186/s41181-021-00141-0

Multivalency in CXCR4 chemokine receptor targeted iron oxide nanoparticles

Baghdadi, N. E., Burke, B. P., Alresheedi, T., Nigam, S., Saeed, A., Almutairi, F., …Archibald, S. J. (2021). Multivalency in CXCR4 chemokine receptor targeted iron oxide nanoparticles. Dalton Transactions : an international journal of inorganic chemistry, 50(5), 1599-1603. https://doi.org/10.1039/d0dt02626c

PI3K inhibition as a novel therapeutic strategy for neoadjuvant chemoradiotherapy resistant oesophageal adenocarcinoma

Edge, S. D., Renard, I., Pyne, E., Li, C., Moody, H., Roy, R., …Pires, I. M. (2021). PI3K inhibition as a novel therapeutic strategy for neoadjuvant chemoradiotherapy resistant oesophageal adenocarcinoma. British Journal of Radiology, 94(1119), https://doi.org/10.1259/bjr.20201191

Towards dual SPECT/optical bioimaging with a mitochondrial targeting, 99mTc(i) radiolabelled 1,8-naphthalimide conjugate

Day, A. H., Domarkas, J., Nigam, S., Renard, I., Cawthorne, C., Burke, B. P., …Pope, S. J. A. (in press). Towards dual SPECT/optical bioimaging with a mitochondrial targeting, 99mTc(i) radiolabelled 1,8-naphthalimide conjugate. Dalton Transactions : an international journal of inorganic chemistry, 49(2), 511-523. https://doi.org/10.1039/c9dt04024b

Synthesis of a porphyrin with histidine-like chelate: an efficient path towards molecular PDT/SPECT theranostics

Yap, S. Y., Savoie, H., Renard, I., Burke, B. P., Sample, H. C., Michue-Seijas, S., …Stasiuk, G. J. (2020). Synthesis of a porphyrin with histidine-like chelate: an efficient path towards molecular PDT/SPECT theranostics. Chemical communications : Chem comm / the Royal Society of Chemistry, 56(75), 11090-11093. https://doi.org/10.1039/d0cc03958f

Project

Funder

Grant

Started

Status

Project

New technology to improve capability for clinical radiopharmaceutical production

Funder

MRC Medical Research Council

Grant

£564,548.00

Started

1 January 2019

Status

Ongoing

Project

Translational Research in the Molecular Imaging Research Centre

Funder

Daisy Appeal

Grant

£45,560.00

Started

1 August 2016

Status

Complete

Project

Positron Emission Tomography research

Funder

Daisy Appeal

Grant

£59,999.00

Started

1 March 2016

Status

Complete

Project

Training scientists to develop and Image materials for Tissue Engineering and Regenerative Medicine (iTERM)

Funder

EC European Commission

Grant

£235,084.00

Started

1 October 2013

Status

Complete

Postgraduate supervision

Prof Archibald welcomes applications in all aspects of medical imaging science and positron emission tomography, particularly

- nuclear imaging (PET and SPECT)

- molecular imaging probe development

- radiochemistry

- use of radiometals

- development of receptor protein targeting (small molecules, peptides and antibodies)

- targeted radionuclides for therapy

- radiopharmacy and translational research

Completed PhDs

- Cheryll Allan (2005)

- Christopher Fisher (2005)

- Gary Nicholson (2006)

- Jon Silversides (2006)

- Amanda Sparke (2008)

- Christopher Welch (2009) (2nd Supervisor)

- Graeme McRobbie (2009)

- Ryan Mewis (2009)

- Abid Khan (2010)

- Rachel Smith (2013)

- Benjamin Burke (2013)

- Naomi Jones (2015) (2nd Supervisor)

- Kati Nicholson (2015)

- Ali Al-Zirgani (2016)

- Neazar Baghdadi (2016)

- Seraj Omar Al-Zahrani (2016)

- Mustafa Al-Yassiry (2016)

- Bassim Wahaab (2016)

- David Millar (2016) (2nd supervisor)

- Shubhanchi Nigam (2017)

- Alicja Kownacka (2017)

Current PhD supervisions

- Zainab Abdallah Al-Ali

- Boon-Uma Jowanarhidi

- Hayley Bignell

- Tahani Alresheedi

- Fada Jabber

- Rhiannon Lee

- Isaline Renard

- Rebecca Ullah (2nd supervisor)

- James Thompson (2nd supervisor)

- Noemi Perujo Holland (2nd supervisor)