Dr Stefano Caserta

Dr Stefano Caserta

Lecturer in Immunology

Faculty and Department

  • Faculty of Health Sciences
  • Hull York Medical School

I am a Fellow of the Higher Education Academy. I take part in teaching and assessment activities in the Biomedical Science Subject Group at the University of Hull. My teaching interests mostly include Immunology and Cellular and Molecular Biology. I take part in lectures, tutorials and one-to-one teaching activities.

I supervised a number of students in the lab in my past career, including many successful researchers and scientists who are now progressing well in their career. If you are a student interested in coming to the lab, please contact me at s.caserta@hull.ac.uk. 

Recent outputs

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Journal Article

Bruton's tyrosine kinase inhibitors impair FcγRIIA-driven platelet responses to bacteria in chronic lymphocytic leukemia

Naylor-Adamson, L., Chacko, A., Booth, Z., Caserta, S., Jarvis, J., Khan, S., …Arman, M. (2021). Bruton’s tyrosine kinase inhibitors impair FcγRIIA-driven platelet responses to bacteria in chronic lymphocytic leukemia. Frontiers in immunology, 12, Article 766272. https://doi.org/10.3389/fimmu.2021.766272

In-Depth Profiling of T-Cell Responsiveness to Commonly Recognized CMV Antigens in Older People Reveals Important Sex Differences

Reus, B., Caserta, S., Larsen, M., Morrow, G., Bano, A., Hallensleben, M., …Kern, F. (2021). In-Depth Profiling of T-Cell Responsiveness to Commonly Recognized CMV Antigens in Older People Reveals Important Sex Differences. Frontiers in immunology, 12, Article 707830. https://doi.org/10.3389/fimmu.2021.707830

Release of redox enzymes and micro-RNAs in extracellular vesicles, during infection and inflammation

Caserta, S., & Ghezzi, P. (2021). Release of redox enzymes and micro-RNAs in extracellular vesicles, during infection and inflammation. Free radical biology & medicine, 169, 248-257. https://doi.org/10.1016/j.freeradbiomed.2021.04.010

Cytomegalovirus infection is associated with an increase in aortic stiffness in older men which may be mediated in part by CD4 memory T-cells

Kirkham, F., Pera, A., Simanek, A. M., Bano, A., Morrow, G., Reus, B., …Kern, F. (in press). Cytomegalovirus infection is associated with an increase in aortic stiffness in older men which may be mediated in part by CD4 memory T-cells. Theranostics, 11(12), 5728-5741. https://doi.org/10.7150/thno.58356

Immune Responses to Persistent or Recurrent Antigens: Implications for Immunological Memory and Immunotherapy

Caserta, S., & Pera, A. (2021). Immune Responses to Persistent or Recurrent Antigens: Implications for Immunological Memory and Immunotherapy. Frontiers in immunology, 12, Article 643989. https://doi.org/10.3389/fimmu.2021.643989

Research interests

I have interests in the areas of infection and tumour immunology, autoimmune disease and ageing. My research at the University of Hull focuses on understanding how T cells differentiate and maintain their function long-term. In particular, intercellular communication in between antigen presenting cells and T cells in humans shapes up the fate of T cells and this can affect the way we respond to pathogens and allergens, potentially making different individuals more or less susceptible to disease. Molecular pathways of intercellular communication between immune cells relevant in infection, critical inflammatory conditions and cancer are currently under investigation.

Co-investigator

Project

Funder

Grant

Started

Status

Project

Using novel endolysins to selectively target antimicrobial resistant S. aureus in chronic wound biofilms

Funder

National Biofilms Innovation Centre

Grant

£105,984.00

Started

1 January 2023

Status

Ongoing

Project

Micreos Contribution to NBIC Studentship

Funder

Micreos Pharma BV

Grant

£20,885.00

Started

1 January 2023

Status

Ongoing

Project

PreclinHUPET2: Enabling Enhanced Preclinical Nuclear Imaging For The North Of England

Funder

MRC Medical Research Council

Grant

£657,700.00

Started

1 February 2023

Status

Complete

Project

Help 4 Health MSc studentships

Funder

Help for Health

Grant

£72,842.00

Started

1 November 2022

Status

Complete

Postgraduate supervision

Infection and Immunity

T cell biology

Cancer Immunology

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