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Professor Matthew Hardman

Chair in Wound Healing / HYMS Director of Research

Faculty and Department

  • Faculty of Health Sciences
  • Hull York Medical School

Summary

Professor Mat Hardman has more than 20 years' experience in the field of skin biology, with a specific focus on wound healing.

His research, which spans basic biology through to clinical studies, has been funded by the Medical Research Council, National Institutes of Health and a number of charities.

His wound healing group engage with a number of industry partners and the Hull University Teaching Hospitals NHS Trust, ensuring a clear route to patient benefit.

Before moving to Hull, Mat was Director of the EPSRC & MRC Centre for Doctoral Training in Regeneration Medicine at the University of Manchester.

Recent outputs

View more outputs

Journal Article

Epithelial arginase-1 is a key mediator of age-associated delayed healing in vaginal injury

Wilkinson, H. N., Reubinoff, B., Shveiky, D., Hardman, M. J., & Menachem-Zidon, O. B. (2022). Epithelial arginase-1 is a key mediator of age-associated delayed healing in vaginal injury. Frontiers in endocrinology, 13, Article 927224. https://doi.org/10.3389/fendo.2022.927224

Skin Aging in Long-Lived Naked Mole-Rats Is Accompanied by Increased Expression of Longevity-Associated and Tumor Suppressor Genes

Fatima, I., Chen, G., Botchkareva, N. V., Sharov, A. A., Thornton, D., Wilkinson, H. N., …Botchkarev, V. A. (in press). Skin Aging in Long-Lived Naked Mole-Rats Is Accompanied by Increased Expression of Longevity-Associated and Tumor Suppressor Genes. Journal of Investigative Dermatology, https://doi.org/10.1016/j.jid.2022.04.028

Combined Metallomics/Transcriptomics Profiling Reveals a Major Role for Metals in Wound Repair

Wilkinson, H. N., Guinn, B. A., & Hardman, M. J. (2021). Combined Metallomics/Transcriptomics Profiling Reveals a Major Role for Metals in Wound Repair. Frontiers in Cell and Developmental Biology, 9, Article 788596. https://doi.org/10.3389/fcell.2021.788596

Human ex vivo wound model and whole-mount staining approach to accurately evaluate skin repair

Wilkinson, H. N., Kidd, A. S., Roberts, E. R., & Hardman, M. J. (2021). Human ex vivo wound model and whole-mount staining approach to accurately evaluate skin repair. Journal of visualized experiments : JoVE, 168, Article e62326. https://doi.org/10.3791/62326

Cellular benefits of single-use negative pressure wound therapy demonstrated in a novel ex vivo human skin wound model

Wilkinson, H. N., Longhorne, F. L., Roberts, E. R., Brownhill, V. R., & Hardman, M. J. (in press). Cellular benefits of single-use negative pressure wound therapy demonstrated in a novel ex vivo human skin wound model. Wound Repair and Regeneration, https://doi.org/10.1111/wrr.12888

Project

Funder

Grant

Started

Status

Project

Development of fully humanised ex vivo human skin wound and infection model

Funder

Animal Free Research UK

Grant

£1,940.00

Started

1 July 2019

Status

Complete

Project

The role of bacteria in the skin: Cold atmospheric plasma for the treatment of pathological skin healing

Funder

British Skin Foundation

Grant

£85,000.00

Started

1 April 2017

Status

Complete

Project

MICA: The role of arginase in chronic delayed wound healing

Funder

MRC Medical Research Council

Grant

£29,842.00

Started

1 August 2016

Status

Complete

Project

Development and application of a new technology for the targeted management of biofilms in human chronic wounds

Funder

Innovate UK

Grant

£29,896.00

Started

1 November 2018

Status

Complete

Postgraduate supervision

Dr Hardman welcomes applications in microbiology, cell biology, wound healing, stem cells, hair follicles and clinical studies.

Completed PhDs

David Ansell, Hair Cycle and Wound Healing.

Elaine Emmerson, Hormonal Modulation of Wound Healing.

Stuart Mills, Photodynamic Therapy for Wound Repair.

Laura Campbell, Immune-modulation of the Wound Response.

Nichola Cooper, PKCalpha and Cell Adhesion in Wound Healing.

Clare Garcin, EDAR Signaling and Hair Follicles in the Wound Response.

Matt Smith, Estrogen Receptor Polymorphisms in Wound Healing.

Chris Saville, Skin Ageing and Hormone Deficiency: Synergistic Interaction in Wound Healing.

Holly Wilkinson, The Role of Metals in Wound Healing.

Current PhD supervisions

Sammi Iveson, Plasma for the Promotion of Wound Healing, 2017-2020.

Daniel Hardy, The Role of Hair Follicles in Wound Healing, 2017-2020.

Paul Weldrick, Novel Antimicrobials for Wound Healing, 2017-2020.

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