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Professor Matthew Hardman

Chair in Wound Healing / HYMS Director of Research

Faculty and Department

  • Faculty of Health Sciences
  • Hull York Medical School

Summary

Professor Mat Hardman has more than 20 years' experience in the field of skin biology, with a specific focus on wound healing.

His research, which spans basic biology through to clinical studies, has been funded by the Medical Research Council, National Institutes of Health and a number of charities.

His wound healing group engage with a number of industry partners and the Hull University Teaching Hospitals NHS Trust, ensuring a clear route to patient benefit.

Before moving to Hull, Mat was Director of the EPSRC & MRC Centre for Doctoral Training in Regeneration Medicine at the University of Manchester.

Recent outputs

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Journal Article

Smart active antibiotic nanocarriers with protease surface functionality can overcome biofilms of resistant bacteria

Weldrick, P. J., Hardman, M. J., & Paunov, V. N. (in press). Smart active antibiotic nanocarriers with protease surface functionality can overcome biofilms of resistant bacteria. Materials Chemistry Frontiers, https://doi.org/10.1039/d0qm00874e

Senescence in Wound Repair: Emerging Strategies to Target Chronic Healing Wounds

Wilkinson, H. N., & Hardman, M. J. (2020). Senescence in Wound Repair: Emerging Strategies to Target Chronic Healing Wounds. Frontiers in Cell and Developmental Biology, 8, https://doi.org/10.3389/fcell.2020.00773

Pre-Clinical Assessment of Single-Use Negative Pressure Wound Therapy During In Vivo Porcine Wound Healing

Brownhill, V., Huddleston, E., Bell, A., Hart, J., Webster, I., Hardman, M., & Wilkinson, H. (in press). Pre-Clinical Assessment of Single-Use Negative Pressure Wound Therapy During In Vivo Porcine Wound Healing. Advances in wound care, . https://doi.org/10.1089/wound.2020.1218

Pre-Clinical Assessment of Single-Use Negative Pressure Wound Therapy During In Vivo Porcine Wound Healing

Brownhill, V. R., Huddleston, E., Bell, A., Hart, J., Webster, I., Hardman, M., & Wilkinson, H. N. (in press). Pre-Clinical Assessment of Single-Use Negative Pressure Wound Therapy During In Vivo Porcine Wound Healing. Advances in wound care, https://doi.org/10.1089/wound.2020.1218

Enhanced Clearing of Wound-Related Pathogenic Bacterial Biofilms Using Protease-Functionalized Antibiotic Nanocarriers

Weldrick, P. J., Hardman, M. J., & Paunov, V. N. (2019). Enhanced Clearing of Wound-Related Pathogenic Bacterial Biofilms Using Protease-Functionalized Antibiotic Nanocarriers. ACS Applied Materials & Interfaces, 11(47), 43902-43919. https://doi.org/10.1021/acsami.9b16119

Project

Funder

Grant

Started

Status

Project

Development of fully humanised ex vivo human skin wound and infection model

Funder

Animal Free Research UK

Grant

£1,940.00

Started

1 July 2019

Status

Complete

Project

The role of bacteria in the skin: Cold atmospheric plasma for the treatment of pathological skin healing

Funder

British Skin Foundation

Grant

£85,000.00

Started

1 April 2017

Status

Complete

Project

MICA: The role of arginase in chronic delayed wound healing

Funder

MRC Medical Research Council

Grant

£29,842.00

Started

1 August 2016

Status

Complete

Project

Development and application of a new technology for the targeted management of biofilms in human chronic wounds

Funder

Innovate UK (use I0075A)

Grant

£29,896.00

Started

1 November 2018

Status

Complete

Postgraduate supervision

Dr Hardman welcomes applications in microbiology, cell biology, wound healing, stem cells, hair follicles and clinical studies.

Completed PhDs

David Ansell, Hair Cycle and Wound Healing.

Elaine Emmerson, Hormonal Modulation of Wound Healing.

Stuart Mills, Photodynamic Therapy for Wound Repair.

Laura Campbell, Immune-modulation of the Wound Response.

Nichola Cooper, PKCalpha and Cell Adhesion in Wound Healing.

Clare Garcin, EDAR Signaling and Hair Follicles in the Wound Response.

Matt Smith, Estrogen Receptor Polymorphisms in Wound Healing.

Chris Saville, Skin Ageing and Hormone Deficiency: Synergistic Interaction in Wound Healing.

Holly Wilkinson, The Role of Metals in Wound Healing.

Current PhD supervisions

Sammi Iveson, Plasma for the Promotion of Wound Healing, 2017-2020.

Daniel Hardy, The Role of Hair Follicles in Wound Healing, 2017-2020.

Paul Weldrick, Novel Antimicrobials for Wound Healing, 2017-2020.