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Dr Leonid Nikitenko

Dr Leonid Nikitenko

Lecturer in Biomedical Sciences

Faculty and Department

  • Faculty of Health Sciences
  • Hull York Medical School

Qualifications

  • PhD

Summary

Dr Leonid Nikitenko is an endothelial cell biologist. His basic and clinical laboratory research is focused on characterising molecular mechanisms regulating endothelial cell function in cancer, cardiovascular disease and lymphoedema.

Alumni from Dr Nikitenko's laboratory and his former tutees at the University of Hull are next generation biomedical scientists who now continue their careers at the Universities of Oxford, Warwick, Manchester and London or in hospitals, the pharmaceutical industry and biotech companies nationwide and abroad.

Google Scholar

https://scholar.google.co.uk/citations?user=ox6Zhu0AAAAJ&hl=en

ResearchGate

https://www.researchgate.net/profile/Leonid_Nikitenko

ResearcherID

https://publons.com/researcher/2621993/leonid-l-nikitenko

Webpage:

http://www.endothelial-cell.com

MSc

Level 7

Research Project and Dissertation

Research Skills in Oncology and Biomedical Science

Current Topics in Biomedical Science

BSc

Level 6

Cancer Biology (module coordinator)

Research Project and Dissertation (40 credit)

Cellular Pathology

Reviews of Biochemistry

Level 5

Biological Basis of Disease

Professional and Research Skills for Biomedical Sciences and Human Biology

Level 4

Cell Structure and Function (module coordinator)

Skills for Biomedical Sciences and Human Biology

Recent outputs

View more outputs

Journal Article

Complex Transcriptional Profiles of the PPP1R12A Gene in Cells of the Circulatory System as Revealed by In Silico Analysis and Reverse Transcription PCR

Saldanha, P. A., Bolanle, I. O., Palmer, T. M., Nikitenko, L. L., & Rivero, F. (2022). Complex Transcriptional Profiles of the PPP1R12A Gene in Cells of the Circulatory System as Revealed by In Silico Analysis and Reverse Transcription PCR. Cells, 11(15), Article 2315. https://doi.org/10.3390/cells11152315

Low molecular weight heparin and direct oral anticoagulants influence tumour formation, growth, invasion and vascularisation by separate mechanisms

Featherby, S., Xiao, Y. P., Ettelaie, C., Nikitenko, L. L., Greenman, J., & Maraveyas, A. (2019). Low molecular weight heparin and direct oral anticoagulants influence tumour formation, growth, invasion and vascularisation by separate mechanisms. Scientific reports, 9(1), Article 6272. https://doi.org/10.1038/s41598-019-42738-1

Other

A Patient's Guide to Pulmonary Fibrosis, Second Edition

Jagielka, K., Hockin, E., Faulkner, E. C., Hart, S., & Nikitenko, L. L. (2022). A Patient's Guide to Pulmonary Fibrosis, Second Edition. [print]

A Patient's Guide to Pulmonary Fibrosis, First Edition

Jagielka, K., Faulkner, E. C., Hart, S., & Nikitenko, L. L. (2020). A Patient's Guide to Pulmonary Fibrosis, First Edition

Working Paper

Integrated single-cell RNA sequencing analysis reveals alterations of ageing human lung endothelium heterogeneity in idiopathic pulmonary fibrosis

Faulkner, E. C., Moverley, A. A., Hart, S. P., & Nikitenko, L. L. Integrated single-cell RNA sequencing analysis reveals alterations of ageing human lung endothelium heterogeneity in idiopathic pulmonary fibrosis

Project

Funder

Grant

Started

Status

Project

EARLY DIAPAC: EARLY DIAgnosis of PAncreatic Cancer by combined proteomics and genomics testing of pancreatic cyst fluid.

Funder

CRUK Cancer Research UK

Grant

£72,818.00

Started

1 December 2022

Status

Ongoing

Postgraduate supervision

Applications from prospective PhD or Masters by Thesis (Research) students wishing to join Dr Nikitenko's research group and thriving postgraduate community at the Centre for Biomedicine at Hull-York Medical School are welcome at any time.

In particular, Dr Nikitenko invites expression of interest and applications in the following areas of research.

- Novel molecular mechanisms regulating endothelial cells properties and function in health and chronic diseases.

- G-protein coupled receptors as targets for imaging and therapy in cardiovascular disease, cancer, lymphoedema and lung disease.

- Platform science approaches (next generation sequencing, label-free quantitative proteomics, high content imaging and bioinformatics) to study endothelial and cancer cell biology.

- Three-dimensional models and gene editing to study the role for endothelial cells in tumour microenvironment in cancer progression.

- Proteomics of lymphatic endothelial cells.

- Cancer progression and resistance to targeted therapies .

- Early diagnosis and detection of cancer.

Membership/Fellowship of professional body

Senior Fellow, Higher Education Academy

2019

Fellow, Royal Society of Biology

2016

Fellow, Institute of Biomedical Science

2016

Active Member, American Association for Cancer Research

2013

Full Member, Biochemical Society

2003

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