Summary
Judith has a BSc in Medical Biochemistry from the University of Leicester, and a PhD in the biochemistry of wound healing from the University of Sheffield. She completed early post-doctoral work at the University of Manchester, before moving into clinical trials at the Wolfson Molecular Imaging Centre. She joined Sheffield Clinical Trials Research Unit (CTRU) in 2007, and developed expertise in clinical trials methodology, including the design and implementation of large scale randomised controlled trials (RCTs).
She was appointed as Director of the Hull Health Trials Unit (HHTU) in November 2017, and as a Clinical Trials methodologist within the University of Hull Institute of Clinical and Applied Health Research (ICAHR) Methods Hub. She led on establishing the HHTU and attaining UKCRC CTU provisional registration (registration number 68). HHTU is an academic-led clinical trials unit which houses a multidisciplinary team with expertise in clinical trial design, conduct and analysis. HHTU works in collaboration with NHS clinicians, academics and industry partners to centrally coordinate multi-centre clinical trials and other well-designed studies including CTIMPs.
MSc Pharmacology and Drug Development, HYMS
Module lead for Bench to Bedside II: Clinical Trials
https://www.hyms.ac.uk/postgraduate-taught/msc-in-pharmacology-and-drug-development
MBBS, HYMS
Seminars and teaching on clinical trials, critical appraisal, ethics and professionalism, health and society
SSIPs
Physician Associate (PA), HYMS
Modules from MSc Pharmacology and Drug Development delivered as part of this course
Journal Article
Complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): a feasibility, wait-list design randomised controlled trial
Crooks, M. G., Wright, C., Hart, S., Allgar, V., English, A., Swan, F., Dyson, J., Richardson, G., Twiddy, M., Cohen, J., Simpson, A., Huang, C., Sykes, D. L., & Johnson, M. (2025). Complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): a feasibility, wait-list design randomised controlled trial. BMJ Open Respiratory Research, 12(1), Article e002327. https://doi.org/10.1136/bmjresp-2024-002327
Exploring COPD patients' and carers' experiences, understandings and expectations of exacerbations: an interview study
Hutchinson, A., Russell, R., Cummings, H., Usmani, O., MacFadyen, S., Cohen, J., Morris, T., Muellerova, H., Xu, Y., Hellens, G., Roy, K., & Crooks, M. G. (2025). Exploring COPD patients’ and carers’ experiences, understandings and expectations of exacerbations: an interview study. BJGP Open, https://doi.org/10.3399/BJGPO.2024.0026
Outcomes in patients treated with loop diuretics without a diagnosis of heart failure: a retrospective cohort study
Cuthbert, J. J., Soyiri, I., Lomax, S. J., Turgoose, J., Fuat, A., Cohen, J., & Clark, A. L. (2024). Outcomes in patients treated with loop diuretics without a diagnosis of heart failure: a retrospective cohort study. Heart, 110(12), 854-862. https://doi.org/10.1136/heartjnl-2023-323577
A randomised controlled trial of Pre-Operative Oncotype DX testing in early-stage breast cancer (PRE-DX study) - Study protocol
Northgraves, M., Cohen, J., Harvey, J., Huang, C., Palmieri, C., Pinder, S., Roy, P., Reynia, S., Soares, M., & Cain, H. (2024). A randomised controlled trial of Pre-Operative Oncotype DX testing in early-stage breast cancer (PRE-DX study) - Study protocol. PLoS ONE, 19(3), Article e0300339. https://doi.org/10.1371/journal.pone.0300339
Modified-release morphine or placebo for chronic breathlessness: the MABEL trial protocol
Date, K., Williams, B., Cohen, J., Chaudhuri, N., Bajwah, S., Pearson, M., Higginson, I., Norrie, J., Keerie, C., Tuck, S., Hall, P., Currow, D., Fallon, M., & Johnson, M. (2023). Modified-release morphine or placebo for chronic breathlessness: the MABEL trial protocol. ERJ Open Research, 9(4), Article 00167. https://doi.org/10.1183/23120541.00167-2023
Research interests
Clinical trials and other well designed applied health research designs
Studies within a trial (SWATs)
The HHTU study portfolio demonstrates success in obtaining funding from a range of funders including NIHR, MRC and Industry partners and expertise across a range of clinical areas, interventions and study designs.
Lead investigator
Project
Funder
Grant
Started
Status
Project
STARLIT: Clinical validation of a non-invasive diagnostic test for adrenal insufficiency using comparative pharmacodynamic equivalence
Funder
MRC Medical Research Council
Grant
£293,574.00
Started
1 September 2022
Status
Ongoing
Project
REMEDI4ALL BUILDING A SUSTAINABLE EUROPEAN INNOVATION PLATFORM TO ENHANCE THE REPURPOSING OF MEDICINES FOR ALL
Funder
Innovate UK
Grant
£922,056.00
Started
1 September 2022
Status
Ongoing
Project
Organic Disease masquerading as IBS: an RCT in primary care: The Lincolnshire Poacher Study (Promoting Optimal Assessment to Change Health and Engineer an Economic Revolution
Funder
NIHR National Institute for Health Research
Grant
£21,708.00
Started
1 June 2020
Status
Complete
Project
Endoscopic vein harvesting - Research Support Funding
Funder
Hull University Teaching Hospitals NHS Trust
Grant
£9,431.00
Started
1 August 2022
Status
Complete
Project
LIPS: A prospective registry-based cohort study to monitor the diagnosis and management of acute leukaemia in pregnancy
Funder
Blood Cancer UK
Grant
£71,112.00
Started
1 June 2018
Status
Complete
Project
North of England Women’s Diet and ActivitY After Breast Cancer Trial (NEW DAY-ABC)
Funder
YCR Yorkshire Cancer Research
Grant
£38,759.00
Started
5 November 2019
Status
Complete
Project
Pre-Operative Oncotype DX testing: A decision impact study (PRE-DX study)
Funder
Exact Sciences
Grant
£365,121.00
Started
1 July 2022
Status
Complete
Project
The Cognitive Daisy (COG-D) for improving care for residents with dementia in care homes: A feasibility RCT
Funder
NIHR National Institute for Health Research
Grant
£39,856.00
Started
1 April 2022
Status
Complete
Project
The North of England Alcohol Team (NEAT)
Funder
NIHR National Institute for Health Research
Grant
£0.00
Started
1 January 2023
Status
Complete
Co-investigator
Project
Funder
Grant
Started
Status
Project
A phase II, randomised feasibility trial of a tailored, home-based exercise programme on disease-free survival among early stage high-risk recurring cancers in Yorkshire
Funder
YCR Yorkshire Cancer Research
Grant
£932,740.00
Started
1 September 2022
Status
Ongoing
Project
Evaluating the effectiveness and acceptability of free door to door transport to increase the uptake of breast screening appointments in Yorkshire: A cluster randomised GP pilot trial
Funder
YCR Yorkshire Cancer Research
Grant
£293,513.00
Started
1 June 2023
Status
Ongoing
Project
Programme of Research for Alcohol Care Teams: Impact, Value and Effectiveness (ProACTIVE -2)
Funder
NIHR National Institute for Health Research
Grant
£778,103.00
Started
1 October 2022
Status
Ongoing
Project
NIHR Policy Research Unit (PRU) for Palliative and End of Life Care
Funder
NIHR National Institute for Health Research
Grant
£770,949.00
Started
1 January 2024
Status
Ongoing
Project
BREEZE 2: A randomised controlled trial of a complex intervention to manage breathlessness in pulmonary fibrosis
Funder
NIHR National Institute for Health Research
Grant
£397,551.00
Started
1 April 2024
Status
Ongoing
Project
DAMPen-D II: Improving the Detection, Assessment, Management, and Prevention of Delirium in Palliative Care Units: a cluster Randomised-Controlled Trial, Economic Analysis and Process Evaluation
Funder
NIHR National Institute for Health Research
Grant
£2,142,656.00
Started
1 October 2024
Status
Ongoing
Project
A collaborative multi-method service evaluation of alcohol assertive outreach in Hull (CoACH)
Funder
NIHR National Institute for Health Research
Grant
£145,600.00
Started
1 January 2023
Status
Ongoing
Project
Yorkshire & Humber ARC - 18M extension (Palliative)
Funder
NIHR National Institute for Health Research
Grant
£30,310.00
Started
1 October 2024
Status
Ongoing
Project
Supportive Care for Persons with Blood Cancers
Funder
Hull University Teaching Hospitals NHS Trust
Grant
£40,000.00
Started
1 November 2023
Status
Ongoing
Project
NIHR Mental Health Research Group
Funder
NIHR National Institute for Health Research
Grant
£8,411,778.00
Started
1 November 2024
Status
Ongoing
Project
NEW DAY-ABC: North of England Women's Diet and ActivitY After Early Breast Cancer (NEWDAY-ABC): hybrid intervention-implementation trial
Funder
YCR Yorkshire Cancer Research
Grant
£1,035,882.00
Started
1 July 2025
Status
Ongoing
Project
CHAMPION: AlCohol HArM PreventIOn iN pregnancy
Funder
NIHR National Institute for Health Research
Grant
£168,068.00
Started
4 January 2021
Status
Complete
Project
The Ulsys “smart sock” – transforming venous leg ulcer care with a patient centred electronically assisted self-care compression system.
Funder
NIHR National Institute for Health Research
Grant
£468.00
Started
16 August 2019
Status
Complete
Project
BREATHE: Breathlessness RElief AT HomE
Funder
NIHR National Institute for Health Research
Grant
£232,098.00
Started
1 April 2019
Status
Complete
Project
Alcohol Dependence Care Pathways
Funder
NIHR National Institute for Health Research
Grant
£45,152.00
Started
1 September 2020
Status
Complete
Project
Adapting a smartphone-based rehabilitation programme for older adults living with and beyond cancer: an intervention development study
Funder
NIHR National Institute for Health Research
Grant
£135,659.00
Started
1 April 2022
Status
Complete
Project
The Yorkshire & Humber Palliative Care Research Network: Addressing Inequalities Across All Ages
Funder
NIHR National Institute for Health Research
Grant
£98,332.00
Started
1 March 2022
Status
Complete
Project
HEIF: Simplifying patient information for clinical trials
Funder
University of Hull
Grant
£22,200.00
Started
1 August 2023
Status
Complete
Postgraduate supervision
Buse Apel – PhD, University of Hull (2019 – present)
Exploring the role of physical activity in the prevention of relapse of service users with alcohol dependence.
Zoe Baldwin - PhD, Hull York Medical School (2022 - present)
What is the most appropriate model of survivorship care for adult patients diagnosed with a haematological malignancy?