Dr Andre Voelzmann

Dr Andre Voelzmann

Lecturer in Cell Biology

Faculty and Department

  • Faculty of Science and Engineering
  • School of Natural Sciences

Summary

After graduating in Biology, André did his PhD in Molecular Biomedicine in Prof. Michael Hoch's lab at the University of Bonn, Germany. He joined Prof. Andreas Prokop's group at the University of Manchester as postdoctoral researcher and was awarded a fellowship of the German Research Foundation in 2015. In 2021, André joined Prof. Alan Dickson's lab at the Manchester Institute of Biotechnology on a collaboration project with Pharmaron Biologics Ltd, UK. In 2023, André joined the Faculty of Science and Engineering/Biological Sciences at the University of Hull where he is a Lecturer in Cell Biology. His research group explores host cell – virus interactions in the context of the manufacture of cell and gene therapies.

André is also Honorary Research Fellow at the University of Manchester and member of cohort 5a of the BioIndustry Association’s Manufacturing Advisory Committee Leadership Programme (BIA MAC LeaP).

Recent outputs

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Book Chapter

Drosophila Primary Neuronal Cultures as a Useful Cellular Model to Study and Image Axonal Transport

Voelzmann, A., & Sanchez-Soriano, N. (2022). Drosophila Primary Neuronal Cultures as a Useful Cellular Model to Study and Image Axonal Transport. In A. Vagnoni (Ed.), Axonal Transport (429-449). New York: Humana Press. https://doi.org/10.1007/978-1-0716-1990-2_23

Journal Article

Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons

Hahn, I., Voelzmann, A., Parkin, J., Fülle, J. B., Slater, P. G., Lowery, L. A., …Prokop, A. (2021). Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons. PLoS Genetics, 17(7), Article e1009647. https://doi.org/10.1371/journal.pgen.1009647

Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age-A nd combination-specific phenotypic profiles in Drosophila

West, R. J., Sharpe, J. L., Voelzmann, A., Munro, A. L., Hahn, I., Baines, R. A., & Pickering-Brown, S. (2020). Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age-A nd combination-specific phenotypic profiles in Drosophila. Acta Neuropathologica Communications, 8(1), Article 158. https://doi.org/10.1186/s40478-020-01028-y

Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex

Qu, Y., Hahn, I., Lees, M., Parkin, J., Voelzmann, A., Dorey, K., …Prokop, A. (2019). Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex. eLife, 8, Article e50319. https://doi.org/10.7554/eLife.50319

The model of local axon homeostasis - Explaining the role and regulation of microtubule bundles in axon maintenance and pathology

Hahn, I., Voelzmann, A., Liew, Y. T., Costa-Gomes, B., & Prokop, A. (2019). The model of local axon homeostasis - Explaining the role and regulation of microtubule bundles in axon maintenance and pathology. Neural Development, 14(1), Article 11. https://doi.org/10.1186/s13064-019-0134-0

Research interests

Dr Voelzmann’s group is interested in optimising the manufacturability of viral vector-based cell and gene therapies. The current research focus lies on understanding producer cell-virus interactions in the context of recombinant Adenoassociated Virus assembly, ssDNA loading, viral trafficking, and viral egress. The aim is to leverage these insights to help optimise gene therapy production on an industrial scale.

Awards and prizes

Doctoral Academy’s Outstanding PostDoc Award, University of Manchester

2021 - 2021

Winner of the Doctoral Academy Excellence Awards as Doctoral Academy’s Outstanding PostDoc of the Year for contribution and achievements in the PGR community in the Faculty of Biology Medicine and Health, University of Manchester.

Honorary position

Honorary Research Fellow in Chemical Engineering, University of Manchester

2023 - 2026

Honorary Research Fellow in Chemical Engineering at the School of Engineering, Faculty of Science and Engineering, University of Manchester

Membership/Fellowship of professional body

Fellow of the Higher Education Academy

2020

Fellowship of the Higher Education Academy awarded in recognition of attainment against the UK Professional Standards Framework for teaching and learning support in higher education.

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