Matthew Hardman

Professor Matthew Hardman

Chair in Wound Healing / HYMS Director of Research

Faculty and Department

  • Faculty of Health Sciences
  • Hull York Medical School

Summary

Professor Mat Hardman has more than 20 years' experience in the field of skin biology, with a specific focus on wound healing.

His research, which spans basic biology through to clinical studies, has been funded by the Medical Research Council, National Institutes of Health and a number of charities.

His wound healing group engage with a number of industry partners and the Hull and East Yorkshire Hospitals NHS Trust, ensuring a clear route to patient benefit.

Before moving to Hull, Mat was Director of the EPSRC & MRC Centre for Doctoral Training in Regeneration Medicine at the University of Manchester.

Journal Article

Elevated local senescence in diabetic wound healing is linked to pathological repair via CXCR2.

Wilkinson, H. N., Clowes, C., Banyard, K. L., Matteuci, P., Mace, K., & Hardman, M. J. (2019). Elevated local senescence in diabetic wound healing is linked to pathological repair via CXCR2. Journal of Investigative Dermatology, 139(5), 1171-1181.e6. https://doi.org/10.1016/j.jid.2019.01.005

Breathing new life into old antibiotics: Overcoming antibacterial resistance by antibiotic-loaded nanogel carriers with cationic surface functionality

Weldrick, P. J., Iveson, S., Hardman, M. J., & Paunov, V. N. (2019). Breathing new life into old antibiotics: Overcoming antibacterial resistance by antibiotic-loaded nanogel carriers with cationic surface functionality. Nanoscale, 11(21), 10472-10485. https://doi.org/10.1039/c8nr10022e

Reduced iron in diabetic wounds: An oxidative stress-dependent role for STEAP3 in extracellular matrix deposition and remodelling

Wilkinson, H. N., Upson, S. E., Banyard, K. L., Knight, R., Mace, K. A., & Hardman, M. J. (2019). Reduced iron in diabetic wounds: An oxidative stress-dependent role for STEAP3 in extracellular matrix deposition and remodelling. Journal of Investigative Dermatology, 139(11), 2368-2377.e7. https://doi.org/10.1016/j.jid.2019.05.014

Tissue iron promotes wound repair via M2 macrophage polarisation and the chemokines CCL17 and CCL22

Wilkinson, H. N., Roberts, E. R., Stafford, A. R., Banyard, K. L., Matteucci, P., Mace, K. A., & Hardman, M. J. (2019). Tissue iron promotes wound repair via M2 macrophage polarisation and the chemokines CCL17 and CCL22. American Journal of Pathology, https://doi.org/10.1016/j.ajpath.2019.07.015

Enhanced Clearing of Wound-Related Pathogenic Bacterial Biofilms Using Protease-Functionalized Antibiotic Nanocarriers

Weldrick, P. J., Hardman, M. J., & Paunov, V. N. (2019). Enhanced Clearing of Wound-Related Pathogenic Bacterial Biofilms Using Protease-Functionalized Antibiotic Nanocarriers. ACS applied materials & interfaces, 11(47), 43902-43919. https://doi.org/10.1021/acsami.9b16119

Postgraduate supervision

Dr Hardman welcomes applications in microbiology, cell biology, wound healing, stem cells, hair follicles and clinical studies.

Completed PhDs

David Ansell, Hair Cycle and Wound Healing.

Elaine Emmerson, Hormonal Modulation of Wound Healing.

Stuart Mills, Photodynamic Therapy for Wound Repair.

Laura Campbell, Immune-modulation of the Wound Response.

Nichola Cooper, PKCalpha and Cell Adhesion in Wound Healing.

Clare Garcin, EDAR Signaling and Hair Follicles in the Wound Response.

Matt Smith, Estrogen Receptor Polymorphisms in Wound Healing.

Chris Saville, Skin Ageing and Hormone Deficiency: Synergistic Interaction in Wound Healing.

Current PhD supervisions

Holly Wilkinson, The Role of Metals in Wound Healing, 2015-2019.

Sammi Iveson, Plasma for the Promotion of Wound Healing, 2017-2020.

Daniel Hardy, The Role of Hair Follicles in Wound Healing, 2017-2020.

Paul Weldrick, Novel Antimicrobials for Wound Healing, 2017-2020.