Summary
After graduating in Biology, André did his PhD in Molecular Biomedicine in Prof. Michael Hoch's lab at the University of Bonn, Germany. He joined Prof. Andreas Prokop's group at the University of Manchester as postdoctoral researcher and was awarded a fellowship of the German Research Foundation in 2015. In 2021, André joined Prof. Alan Dickson's lab at the Manchester Institute of Biotechnology on a collaboration project with Pharmaron Biologics Ltd, UK. In 2023, André joined the Faculty of Science and Engineering/Biological Sciences at the University of Hull where he is a Lecturer in Cell Biology. His research group explores host cell – virus interactions in the context of the manufacture of cell and gene therapies.
André is also Honorary Research Fellow at the University of Manchester and was a member of cohort 5a of the BioIndustry Association’s Manufacturing Advisory Committee Leadership Programme (BIA MAC LeaP) from 2021 to 2023.
Book Chapter
Journal Article
Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons
Hahn, I., Voelzmann, A., Parkin, J., Fülle, J. B., Slater, P. G., Lowery, L. A., Sanchez-Soriano, N., & Prokop, A. (2021). Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons. PLoS Genetics, 17(7), Article e1009647. https://doi.org/10.1371/journal.pgen.1009647
Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age-A nd combination-specific phenotypic profiles in Drosophila
West, R. J., Sharpe, J. L., Voelzmann, A., Munro, A. L., Hahn, I., Baines, R. A., & Pickering-Brown, S. (2020). Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age-A nd combination-specific phenotypic profiles in Drosophila. Acta Neuropathologica Communications, 8(1), Article 158. https://doi.org/10.1186/s40478-020-01028-y
Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex
Qu, Y., Hahn, I., Lees, M., Parkin, J., Voelzmann, A., Dorey, K., Rathbone, A., Friel, C. T., Allan, V. J., Okenve-Ramos, P., Sanchez-Soriano, N., & Prokop, A. (2019). Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex. eLife, 8, Article e50319. https://doi.org/10.7554/eLife.50319
The model of local axon homeostasis - Explaining the role and regulation of microtubule bundles in axon maintenance and pathology
Hahn, I., Voelzmann, A., Liew, Y. T., Costa-Gomes, B., & Prokop, A. (2019). The model of local axon homeostasis - Explaining the role and regulation of microtubule bundles in axon maintenance and pathology. Neural Development, 14(1), Article 11. https://doi.org/10.1186/s13064-019-0134-0
Research interests
Dr Voelzmann’s group is interested in optimising the manufacturability of viral vector-based cell and gene therapies. The current research focus lies on understanding producer cell-virus interactions in the context of recombinant Adeno-Associated Virus assembly (rAAV), ssDNA loading, viral trafficking, and viral egress. The aim is to leverage these insights to help optimise gene therapy production on an industrial scale.
If you are interested in a self-funded Masters by Research project, please get in contact.
Lead investigator
Project
Funder
Grant
Started
Status
Project
C-Trap for the North East
Funder
Biotechnology & Biological Sciences Research Counc
Grant
£0.00
Started
1 August 2024
Status
Ongoing
Project
Vice Chancellor PhD Scholarship - Identification of host cell factors involved in Gene Therapy production
Funder
University of Hull
Grant
£0.00
Started
16 September 2024
Status
Ongoing
Co-investigator
Project
Funder
Grant
Started
Status
Project
RISE: Establishing super-Resolution Imaging in Hull for impactful multimorbidity ReSEarch MRC Equipment bid 2024 - Confocal Imaging ZEISS Elyra 7 with Lattice SIM²
Funder
Medical Research Council
Grant
£718,262.00
Started
1 October 2024
Status
Ongoing
Project
Wolfson Equipment bid 2023 - Confocal Imaging ZEISS Elyra 7 with Lattice SIM²
Funder
Wolfson Foundation
Grant
£500,000.00
Started
1 October 2024
Status
Ongoing