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PhD Scholarships

Supramolecular nanoconstructs for positron emission tomography imaging and radioguided surgery

Funding:

Funded PhD

Duration:

3 years (full-time) 6 years (part-time)

Application deadline:

Friday 10 February 2023

About this project

Applications are invited for a PhD project in radiopharmaceutical development and preclinical medical imaging.

Based in the Hull York Medical School, the successful applicant will focus on the development of novel positron emission tomography (PET) radiopharmaceuticals. Biological targeting groups will be combined with motifs (chelators and prosthetic groups) to form bio conjugates for facile radiolabelling as new supramolecular PET imaging agents. Multivalent galectin binding agents will be investigated using a range of techniques including immunohistochemistry and surface plasmon resonance. Radiolabelling studies to produce novel radiopharmaceuticals will be carried out in the dedicated radiotracer development facilities offering unique opportunities to develop skills in radiopharmaceutical validation. In vivo imaging and interaction with clinical colleagues will be used to select lead candidates for translation and potential application in radio-guided surgery.

For informal inquiries, please contact the primary supervisor for this project - Prof Steve Archibald.

About the research cluster

The scholarship forms part of a PhD cluster supporting a major research project funded by the Engineering and Physical Sciences Research Council (EPSRC). This is a joint project with Imperial College London and King’s College London and is also supported by industrial partners.

The successful applicant will benefit from working alongside investigators across the Chemistry Department and the PET Research Centre (part of the Hull Molecular Imaging Centres development (HuMIC) at UoH), as well as with collaborators at Imperial College London and King’s College London. The postgraduate researcher will form an important and integral part of the project team, driving this exciting multidisciplinary and impactful research forward. They will be able to present their work on academic platforms, co-author papers, and work closely with our project industry partners. They will also benefit from close collaboration with the UoH-Medical Research Council CiC interdisciplinary mini-PhD cluster “Immune cell markers in chronic disease” and the ”Hull University Theragnostics” PhD cluster.

HuMIC is a single operational unit formed in 2022, bringing together three centres; Positron Emission Tomography Research Centre (PETRC), Molecular Imaging Research Centre (MIRC) and Jack Brignall PET-CT Centre. It was developed and is led jointly between Daisy Appeal (a local Charitable Trust) and the UoH to provide research and clinical facilities for researchers. The Molecular Imaging Research Centre building (GMP radiotracer) will be fully operational by early 2023 providing a second cyclotron for radioisotope production in Hull. This collaboration is the first worldwide to implement a translational PET strategy based on dose-on-demand PET radiotracer production.

Submission of thesis

Submission of your final thesis is expected within three years and three months from the start of your PhD scholarship for full time and within six years and six months if studying part-time.

Research training

As a PhD student at Hull York Medical School, you will receive comprehensive research training and support. 

How to apply

You will need to supply a personal statement when applying for this scholarship position. Find out more about writing a personal statement. Please also ensure you include the following information:

  • What motivates you to pursue PhD study
  • Why you are interested in this project
  • How your skill set matches the requirements for your choice of project and/or any additional training you will need
  • The wider significance of research in this area and potential future research directions for the project.

Please note that applications to the Hull York Medical School are processed via the University of York admission system. Visit this page for more information on applying to York.

Apply for the scholarship

Closing date for applications

Friday 10 February 2023

Postgraduate Rebecca Humphries & Georgia Sykes walking by HUBS Wharfe Building

University of Hull's Doctoral College provides support to postgraduate research students. Offering skills development opportunities and dedicated facilities, the college is here to help you achieve your potential.

Funding

  • The successful applicants will receive a fee waiver and a maintenance grant / stipend for three years (full-time) or five years (part-time), which covers the research period of the PhD. The fee waiver for 22/23 is £4596 (Home fee) and the maintenance grant is £17668 per annum. This rises each year in line with the UKRI’s recommended stipend allowance.

  • If you need to move into a fourth year (full time) or sixth year (part-time) to complete your thesis, please note that you will not receive a tuition fee waiver or maintenance grant during this period and you will be required to pay a continuation fee.

Entry requirements

Applicants should have a minimum 2.1 class of degree in Chemistry, Biochemistry, Biomedical Sciences or a closely related subject.

For more details on our entry requirements please visit the postgraduate admissions webpage.

This scholarship is available for full-time and part-time study.

International applicants

This opportunity comes with a Home fee waiver only, which will not cover the full International fee. You will therefore need to pay the difference between the Home fee and the International fee and will need to provide evidence that you have sufficient funds to cover this, as no additional funding is available.

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