Dr Azeem Saleem

Dr Azeem Saleem

Reader and Honorary Consultant in Clinical Oncology

Faculty and Department

  • Faculty of Health Sciences
  • Hull York Medical School

Qualifications

  • MD
  • PGDip
  • PhD / DPhil (Imperial College London)
  • MD

Summary

I am a Clinical Oncologist by training with a research doctorate in molecular imaging. I have a wide range of experience having worked for the NHS, academia and industry. I qualified in medicine (MB BS) from Madras University, India and completed a post graduate diploma in radiotherapy (DMRT) in 1991. My specialist training in clinical oncology was completed in Merseyside, UK being admitted as a Fellow of the Royal College of radiologists (FRCR) in 2004 and registered as a Clinical Oncologist in the General Medical Council Specialist Register. Between 1997 and 2000, I did my research fellowship at the Medical Research Council (MRC) Cyclotron Unit, Hammersmith Hospital, London between 1997 and 2000, evaluating the utility of positron emission tomography (PET) in anti-cancer drug development to obtain my PhD.

I was a Senior Clinical Research Fellow at the University of Manchester Wolfson Molecular Imaging Centre and an Honorary Consultant in Clinical Oncology at the Christie Hospital between 2005 and 2009. In 2009, I joined the GlaxoSmithKline Clinical Imaging Centre at the Hammersmith Hospital to lead the oncology imaging programme and as an honorary senior clinical lecturer at Imperial College. From 2011 to 2017, I headed oncology and respiratory medicine at Imanova Centre for Imaging Sciences, an Imperial College, University College London, Kings College London and MRC joint venture which aimed to provide imaging expertise to academia and commercial organisations. From 2018, I was the UK Head of Oncology at Invicro, a Konica Minolta Company.

In December 2019, I joined the Hull York Medical School and the University of Hull. I am the Clinical Research Lead at the Hull Molecular Imaging Centres (HuMIC), a > £15 million investment by the Daisy Charity Appeal together with the University of Hull and the Hull University Teaching Hospitals NHS Trust, developed to support radiotracer discovery and translational imaging at Hull. I am also an honorary consultant at the Hull University Teaching Hospital NHS Trust with a specialist practice in pulmonary oncology.

Teaching of Medical Students

Recent outputs

View more outputs

Journal Article

Specificity of translocator protein-targeted positron emission tomography in inflammatory joint disease

Helo, Y., Searle, G. E., Borghese, F., Abraham, S., & Saleem, A. (2020). Specificity of translocator protein-targeted positron emission tomography in inflammatory joint disease. EJNMMI Research, 10(1), Article 147. https://doi.org/10.1186/s13550-020-00736-9

Advanced imaging for quantification of abnormalities in the salivary glands of patients with primary Sjögren's syndrome

Jimenez-Royo, P., Bombardieri, M., Ciurtin, C., Kostapanos, M., Tappuni, A. R., Jordan, N., …Tarzi, R. (2021). Advanced imaging for quantification of abnormalities in the salivary glands of patients with primary Sjögren's syndrome. Rheumatology, 60(5), 2396-2408. https://doi.org/10.1093/rheumatology/keaa624

A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvβ6 integrin inhibitor

Maher, T. M., Simpson, J. K., Porter, J. C., Wilson, F. J., Chan, R., Eames, R., …Vahdati-Bolouri, M. (2020). A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvβ6 integrin inhibitor. Respiratory Research, 21(1), Article 75. https://doi.org/10.1186/s12931-020-01339-7

Integrin αvβ6 Positron Emission Tomography Imaging in Lung Cancer Patients Treated With Pulmonary Radiation Therapy

Saleem, A., Helo, Y., Win, Z., Dale, R., Cook, J., Searle, G. E., & Wells, P. (2020). Integrin αvβ6 Positron Emission Tomography Imaging in Lung Cancer Patients Treated With Pulmonary Radiation Therapy. International journal of radiation oncology, biology, physics, 107(2), 370-376. https://doi.org/10.1016/j.ijrobp.2020.02.014

Clinical quantification of the integrin αvβ6 by [18F]FB-A20FMDV2 positron emission tomography in healthy and fibrotic human lung (PETAL Study)

Lukey, P. T., Coello, C., Gunn, R., Parker, C., Wilson, F. J., Saleem, A., …Marshall, R. P. (2020). Clinical quantification of the integrin αvβ6 by [18F]FB-A20FMDV2 positron emission tomography in healthy and fibrotic human lung (PETAL Study). European journal of nuclear medicine and molecular imaging, 47(4), 967-979. https://doi.org/10.1007/s00259-019-04586-z

Research interests

Molecular Imaging

Positron Emission Tomography

Novel radio-tracer development

First in Human Studies

Drug development

Lung cancer

Radiotherapy Research

Co-investigator

Project

Funder

Grant

Started

Status

Project

CageTag: Caged Theranostics as a Universal Platform for Nuclear Medicine

Funder

EPSRC Engineering & Physical Sciences Research Council

Grant

£481,520.00

Started

1 April 2022

Status

Ongoing

Project

PreclinHUPET2: Enabling Enhanced Preclinical Nuclear Imaging For The North Of England

Funder

MRC Medical Research Council

Grant

£657,700.00

Started

1 February 2023

Status

Complete

Project

Measuring the travel burden from attending radiotherapy treatment. Testing a bespoke mobile phone application with cancer patients

Funder

University of York

Grant

£6,000.00

Started

1 October 2022

Status

Complete

Committee/Steering group role

Cancer Radiotherapy Sub speciality lead for Yorkshire and Humber

2022

Member, National Cancer Research Institute Working Group

2022

Member of Working Group 2 that will "Publish a roadmap/position paper on the barriers and challenges in molecular radiotherapy research"

Ethics role

London Harrow Research Ethics Committee - Member

2021

Membership/Fellowship of professional body

Member, European Society of Therapeutic Radiation Oncology

2021

Fellow of the Royal College of Radiologists

2004

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