Dr Patrick Harrison

Lecturer in Biochemistry

Faculty of Science and Engineering

patrick.harrison@hull.ac.uk

Dr Harrison was appointed to a lectureship in biochemistry in March 2018 and mainly contributes to the delivery and teaching of BSc/MBiochem Biochemistry.

His research focuses on the development of novel antimicrobial drugs from natural sources, along with the mechanism of action of antimicrobial peptides.

This research uses a variety of techniques across the disciplines of microbiology, protein biochemistry, mammalian cell culture and biophysics.

Dr Harrison has national (Sheffield Hallam University, University of Leeds) and international (Suez Canal University, Egypt) collaborations in these areas.

 

Research

Research Interests

  • Antimicrobial drug development
  • Antimicrobial peptides
  • Protein-lipid interactions
  • Developing analytical methods for the brewing industry
  • The microbiome

Research groups

  • Biochemistry natural products research group (Dr Huw Jones)

Publications

GR Heath, PL Harrison, PN Strong, SD Evans & K Miller. 2018. Visualization of diffusion limited antimicrobial peptide attack on supported lipid membranes. Soft Matter. 14(29):6146-6154

PL Harrison, T Harrison, I Stockley, TJ Smith. 2017. Tantalum does not exhibit any in vitro antimicrobial effects. Bone & Joint Journal. 99-B (9):1153-1156

PL Harrison, Abdel-Rahman MA, PN Strong, MM Tawfik, K Miller. 2016. Characterisation of three alpha-helical antimicrobial peptides from the venom of Scorpio maurus palmatus. Toxicon. 117: 30-36.

PL Harrison, GR Heath, BRG Johnson, Abdel-Rahman MA, PN Strong, SD Evans & K Miller. 2016. Phospholipid dependent mechanism of smp24, an α-helical antimicrobial peptide from scorpion venom. Biochim Biophys Acta. 1858 (11): 2737–2744

PL Harrison, Abdel-Rahman MA, PN Strong & K Miller. 2014. Antimicrobial peptides from scorpion venoms. Toxicon. 88: 115-37

Full list

Teaching

Programmes taught on (2019)

Modules list

Year 1

  • Insights into Biochemistry
  • Chemistry Global Challenge
  • Organic Chemistry Laboratory Sessions

Year 2

  • Biochemistry and Professional Skills 1
  • Biochemistry and Professional Skills 2

Year 3

  • Biochemistry Group Project
  • Advanced Topics in Biochemistry
  • Reviews in Biochemistry
  • Topics in Core Biochemistry
  • Analytical and Forensic Science 2
  • Analytical Laboratory Sessions (coordinator)

Year 4

  • Recent Developments in Biochemistry
  • Research Projects
  • Advanced (Bio)chemistry (module lead)

Professional highlights

Academic qualifications

  • BSc Cellular AND Molecular biology, Sheffield Hallam University (2010)
  • PhD Biochemistry, Sheffield Hallam University (2014)