Michael Fagan

Professor Michael Fagan

Professor of Medical and Biological Engineering

Faculty and Department

  • Faculty of Science and Engineering
  • Department of Engineering

Summary

Professor Fagan is Professor Medical and Biological Engineering and research lead for Biomedical Engineering research in the Department of Engineering. His expertise lies is in modelling and simulation in biomechanics and biomedical engineering using finite element analysis and multibody dynamics analysis.

He is particularly interested in computational mechanobiology to understand the form and function of bone(s) using mathematical and advanced modelling techniques, at the cellular, tissue and whole bone level, with a special interest in skull biomechanics (with Dr Peter Watson). This includes fundamental investigations into the form and function of different skull types, as well as more applied craniofacial research examining craniosynostosis, dental biomechanics and cleft lip and palate, and most recently BBSRC-funded 3Rs research to provide alternatives to animal experiments.

Professor Fagan’s other research interests include wound management research (with Dr Louise France) and he has been working with Smith and Nephew Wound Management (Hull) for more than 12 years. This collaboration culminated in the establishment of a university-wide wound care cluster between the University and S&N in 2018.

Finally, as part of a multi-centre EPSRC Prosperity Partnership on offshore wind, Professor Fagan is applying biomimetic principles to wind turbine blade design and examining whether cancellous bone-like structures could be used in next generation blade design.

Professor Fagan’s multidisciplinary research funding comes from a wide variety of society, including Action Medical Research, BBSRC, EPSRC, EU, NERC, the Royal Society and Wellcome Trust.

Journal Article

Bite force and cranial bone strain in four species of lizards

Ross, C. F., Porro, L. B., Herrel, A., Evans, S. E., & Fagan, M. J. (2018). Bite force and cranial bone strain in four species of lizards. The journal of experimental biology, 221(23), jeb.180240. https://doi.org/10.1242/jeb.180240

Mathematical modelling of bone remodelling cycles including the NF?B signalling pathway

Ji, B., Zhang, Y., Zhen, C., Fagan, M. J., & Yang, Q. (2019). Mathematical modelling of bone remodelling cycles including the NF?B signalling pathway. Computers in biology and medicine, 107, 257-264. https://doi.org/10.1016/j.compbiomed.2019.03.003

Characterizing and Modeling Bone Formation during Mouse Calvarial Development

Marghoub, A., Libby, J., Babbs, C., Ventikos, Y., Fagan, M. J., & Moazen, M. (2019). Characterizing and Modeling Bone Formation during Mouse Calvarial Development. Physical review letters, 122(4), https://doi.org/10.1103/PhysRevLett.122.048103

A 3D cephalometric protocol for the accurate quantification of the craniofacial symmetry and facial growth

Pinheiro, M., Ma, X., Fagan, M. J., McIntyre, G. T., Lin, P., Sivamurthy, G., & Mossey, P. A. (2019). A 3D cephalometric protocol for the accurate quantification of the craniofacial symmetry and facial growth. Journal of Biological Engineering, 13(1), https://doi.org/10.1186/s13036-019-0171-6

Neurocranial development of the coelacanth and the evolution of the sarcopterygian head

Dutel, H., Galland, M., Tafforeau, P., Long, J. A., Fagan, M. J., Janvier, P., …Herbin, M. (2019). Neurocranial development of the coelacanth and the evolution of the sarcopterygian head. Nature, 569, 556–559. https://doi.org/10.1038/s41586-019-1117-3

Project

Funder

Grant

Started

Status

Project

Prosperity Partnerships: EPSRC, Business and Universities

Funder

EPSRC Engineering & Physical Sciences Research Council

Grant

£526,429.00

Started

1 November 2017

Status

Ongoing

Project

Speech Rehabilitation from Articulator Movement (SRAM)

Funder

NIHR National Institute for Health Research

Grant

Started

1 January 2016

Status

Complete