Torch

Dr Isabel Monteiro dos Santos Pires

Lecturer in Biomedical Science/ Head of the Hypoxia and Tumour Microenvironment group

Faculty and Department

  • Faculty of Health Sciences
  • School of Life Sciences

Summary

Dr Isabel Pires is a cancer biologist, and particularly interested in how low oxygen (hypoxia) in tumours impacts on metastatic spread and therapy.

She is an enthusiastic science communicator, and has given talks in such events as TEDx Hull and Pint of Science. She is the main organiser of Soapbox Science Hull.

Dr Pires is passionate about training the next generation of scientists. She a member of the executive committee of the British Association for Cancer Research, and an ambassador of the Biochemical Society at Hull, as well as a member of their training panel.

Undergraduate

MSc

- Cellular and Molecular Biology of Cancer (module coordinator)

- Tumour Immunology and Microenvironment (module coordinator)

- Organ-specific Cancers

- Research Skills

- Current Topics in Biomedical Science

- Research Project and Dissertation

BSc

- Skills for Biomedical Science

- Biological Basis of Disease

- Cancer Biology

- Research Project and Dissertation

Book

The Secret Science of Superheroes

M. Lorch, & A. Miah (Eds.), (2016). The Secret Science of Superheroes

Journal Article

Natural Products as a Source for New Leads in Cancer Research and Treatment

Cabral, C., Efferth, T., Pires, I. M., Severino, P., & Lemos, M. F. (2018). Natural Products as a Source for New Leads in Cancer Research and Treatment. Evidence-based complementary and alternative medicine : eCAM, 2018, 1-2. https://doi.org/10.1155/2018/8243680

WSB-1 regulates the metastatic potential of hormone receptor negative breast cancer

Poujade, F., Mannion, A., Brittain, N., Theodosi, A., Beeby, E., Leszczynska, K. B., …Pires, I. M. (2018). WSB-1 regulates the metastatic potential of hormone receptor negative breast cancer. The British journal of cancer / Cancer Research Campaign, 118(9), 1229-1237. https://doi.org/10.1038/s41416-018-0056-3

Signaling by PTK6

Orlic-Milacic, M., & Pires, I. (2016). Signaling by PTK6. Reactome a knowledgebase of biological processes, 56, doi:10.3180/r-hsa-8848021.1

Anticancer properties of essential oils and other natural products

Blowman, K., Magalhães, M., Lemos, M. F., Cabral, C., & Pires, I. M. (2018). Anticancer properties of essential oils and other natural products. Evidence-based complementary and alternative medicine : eCAM, 2018, 1-12. https://doi.org/10.1155/2018/3149362

Postgraduate supervision

Please contact Dr Pires directly if you are interested in joining her group. She welcomes applications/expressions of interest in the following:

- Novel players in the biology of the tumour microenvironment (particular focus on metastasis)

- Targeting the tumour microenvironment

- Cancer biology, especially breast, colorectal, lung, and oesophageal cancer

- Cancer therapy, especially radiotherapy and targeted therapies

- Modelling the tumour microenviromnment, including 3D models of cancer and lab-on-a-chip

Completed PhDs

- Flore-Anne Poujade (2013-2016) - as primary supervisor

- Anna Todd (2013-2016) - as primary supervisor

Current PhD supervisions

- Thomas Collins (2015-2018) - as primary supervisor

- Sarah Argyle (2015-2018) - as primary supervisor

Current MSc-Res supervisions

- Merce Gomez-Merchan (2017-2018) - as primary supervisor