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Dr Huw Jones

Lecturer in Biochemistry

Faculty and Department

  • Faculty of Science and Engineering
  • School of Mathematics and Physical Sciences

Summary

Dr Jones is a lecturer in biochemistry, with research interests in the modulation of health and disease states by natural products. He is particularly interested in how chemicals found within the diet can act as medicinal drugs, particularly in terms of modulating redox signaling and oxidative stress. This research uses a variety of cell culture models, in addition to collaborations with clinicians and physiologists, to undertake research at the tissue and human levels. Dr Jones contributes to the delivery and teaching of BSc / MBiochem Biochemistry, and delivers lectures on biochemistry as part of the MSc in Clinical Exercise Physiology.

Undergraduate

Year 1 - Insights into biochemistry (biochemistry) - Introduction to DNA and chromatography Year 2 - Biochemistry and professional skills 1 (biochemistry) - Biochemistry and professional skills 2 (biochemistry) - Forensic science in practice Year 3 - Biochemistry group project (biochemistry) - Advanced topics in biochemistry (biochemistry) - Reviews in biochemistry (biochemistry) Year 4 - Biochemistry of health and disease

Journal Article

Oxidized LDL activates blood platelets through CD36/NOX2–mediated inhibition of the cGMP/protein kinase G signaling cascade

Magwenzi, S., Woodward, C., Wraith, K. S., Aburima, A., Raslan, Z., Jones, H., …Naseem, K. M. (2015). Oxidized LDL activates blood platelets through CD36/NOX2–mediated inhibition of the cGMP/protein kinase G signaling cascade. Blood, 125(17), 2693-2703. doi:10.1182/blood-2014-05-574491

The dietary flavonol quercetin ameliorates angiotensin II-induced redox signaling imbalance in a human umbilical vein endothelial cell model of endothelial dysfunction via ablation of p47???? expression

Jones, H. S., Gordon, A., Magwenzi, S. G., Naseem, K., Atkin, S. L., & Courts, F. L. (2016). The dietary flavonol quercetin ameliorates angiotensin II-induced redox signaling imbalance in a human umbilical vein endothelial cell model of endothelial dysfunction via ablation of p47???? expression. Molecular Nutrition and Food Research, 60(4), 787-797. https://doi.org/10.1002/mnfr.201500751

Pilot investigation of a virtual gastric band hypnotherapy intervention

Greetham, S., Goodwin, S., Wells, L., Whitham, C., Jones, H., Rigby, A., …Atkin, S. (2016). Pilot investigation of a virtual gastric band hypnotherapy intervention. International Journal of Clinical and Experimental Hypnosis, 64(4), 419-433. https://doi.org/10.1080/00207144.2016.1209037

The effects of acute interval exercise and strawberry intake on postprandial lipemia

O’Doherty, A., Jones, H. S., Sathyapalan, T., Ingle, L., & Carroll, S. (2017). The effects of acute interval exercise and strawberry intake on postprandial lipemia. Medicine and Science in Sports and Exercise, 49(11), 2315-2323. https://doi.org/10.1249/MSS.0000000000001341

Postgraduate supervision

Dr Jones welcomes applications in - pharmacological effects of natural products in health and disease states - analytical approaches to the measurement of reactive oxygen species and oxidative stress markers - novel methods for the synthesis of human circulating metabolites of xenobiotics and natural products Completed PhDs - Eleanna Chalari (as co-supervisor), The effects of intermittency and acceleration on exercise-induced oxidative stress after high-intensity intermittent exercise (2017) Current PhD supervisions - Nikki Simpson, Effect of coenzyme Q10 supplementation upon skeletal muscle oxidative signaling in vitro and in vivo (as co-supervisor) - Rachel Burke, Nitrate supplementation and vascular function (as co-supervisor)