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WELCOME ...

to the website of the Medical and Biological Engineering research group at the University of Hull, based in the Department of Engineering. 

Our work is focused on computational biomedical and biological engineering research, with current and recent supporters of our research including BBSRC, EPSRC, MRC, NERC Department of Health, Leverhulme Trust, Royal Society, Action Medical Research, Yorkshire Forward and others.

The key technologies that we apply are finite element analysis and multibody dynamics analysis, with complex image and data processing, where core input data is provided by microCT, nanoindenter, DMA and direct experimental measurements.

A key activitiy is the modelling of bone, to understand its form and function - at all levels. The group has a special interest in the modelling of skulls to examine how mechanical environment affects primate skull morphology and the relationship between the biomechanics and evolution of tetrapod skulls. 

We also work on computer assisted diagnostics, especially predicting the risk of rupture of abdominal aortic aneurysms by patient-specific finite element analysis, and including the development of software for automatic extract of aneurysm geometries from clinical CT scans.

And lastly, we are involved in medical device development - in particular development of solutions for patients following laryngectomy. 


We are based in the purpose-built Medical Engineering Labs at the University of Hull.


LATEST PUBLICATIONS

N Curtis, M Jones, SE Evans, P O'Higgins, MJ Fagan. 2009. Predicting muscle activation patterns from motion and anatomy: modelling the skull of Sphenodon (Diapsida: rhynchocephalia).
Journal of the Royal Society Interface, DOI:10.1098/rsif.2009.0139 VIEW

J McLeod, N Curtis, HD Lewis, MA Good, MJ Fagan, P Genever. 2009. Gamma-secretase-dependent cleavage of amyloid precursor protein regulates osteoblast behaviour.
The FASEB Journal, DOI:10.1096/fj.08-121657 VIEW

F Gröning, J Liu, MJ Fagan, P O'Higgins. 2009. Validating a voxel-based finite element model of a human mandible using digital speckle pattern interferometry.
Journal of Biomechanics. 42, 1224-1229. VIEW

K Kupczik, CA Dobson, RH Crompton, R Phillips, CE Oxnard, MJ Fagan, P O'Higgins. 2009. Masticatory loading and bone adaptation in the supraorbital torus of developing macaques.
American Journal of Physical Anthropology, 139, 193-203. VIEW

M Moazen, N Curtis, SE Evans, P O'Higgins, MJ Fagan. 2009. Biomechanical assessment of evolutionary changes in the lepidosaurian skull.
Proc Natl Acad Sci USA, 20, 8273-8277. VIEW

M Moazen, N Curtis, P O'Higgins, MEH Jones, SE Evans, MJ Fagan. 2009. Assessment of the role of sutures in a lizard skull - a computer modelling study.
Proceedings of the Royal Society, Part B, 276, 39-46. VIEW

more ...  

   

mac
   
   
iguana
     
   
animated macaque
     
  
trabecular bone

teeth_CT
    
aneurysms
    
   
microCT bone in-growth