Steve Archibald-min

Professor Steve J Archibald

Professor in Molecular Imaging Chemistry

Faculty of Science and Engineering

School of Mathematics and Physical Sciences

s.j.archibald@hull.ac.uk

01482 465488

Research areas in the Archibald group are PET probe development, chemokine receptor imaging and lab-on-a-chip/ microfluidic devices for radiosynthesis and quality control.

Prof Archibald was awarded a first class BSc degree in Chemistry, Life Systems and Pharmaceuticals by the University of York in 1992 and a PhD in Chemistry by the University of Edinburgh in 1995.

He carried out postdoctoral research at the Universities of Paris-Sud (France), Kansas (USA) and York (UK), before being appointed as a lecturer at the University of Hull in 2000.

Prof Archibald was promoted to Senior Lecturer in 2008, Reader in 2011, Director of the Positron Emission Tomography Research Centre in 2013 and Professor in 2014.

 

Research

Research Interests

  • Radiopharmaceutical imaging (positron emission tomography)

  • Positron Emission Tomography

Research groups

Director of the University's Positron Emission Tomography Research Committee

Part of the EU FP7 International Training Network, ‘iTERM: imaging for tissue engineering ITN’

Member of

  • EU COST Action TD1007 Bimodal PET-MRI Molecular Imaging Technologies (2013-2016)

  • EU COST Action TD1402 Multifunctional Nanoparticles for Magnetic Hyperthermia and Indirect Radiation Therapy (2015-present)

Publications

Archibald S J et al, 'Structurally Optimised BODIPY Derivatives for Imaging of Mitochondrial Dysfunction in Cancer and Heart Cells, Chemical Communications, 52, pp 7114–7117 (2016)

Archibald S J et al, 'Positron Detection in Silica Monoliths for Miniaturised Quality Control of PET Radiotracers, Chemical Communications, 52, pp 7221–7224 (2016)

Archibald S J et al, 'Chelator Free Gallium-68 Radiolabelling of Silica Coated Iron Oxide Nanorods via Surface Interactions', Nanoscale, 7, pp 14889-14896 (2015)

Burke B P, Clemente G and Archibald S J, 'Recent Advances in Chelator Design and Labelling Methodology for 68Ga Radiopharmaceuticals', Journal of Labelled Compounds and Radiopharmaceuticals, 239 (2014)

Archibald S J et al, 'Binding Optimisation through Coordination Chemistry: CXCR4 Chemokine Receptor Antagonists from Ultrarigid Metal Complexes', Journal of the American Chemical Society, 131, pp 3416-3417 (2009)

Full list

Teaching

Programmes taught on

Modules list

  • Medical Imaging Chemistry

  • Anti-Cancer Drug Design

  • Introduction to Bioinorganic Chemistry

  • Bioinorganic and Medicinal Inorganic Chemistry

  • Supramolecular Chemistry

Research PhDs

Prof Archibald welcomes applications in all aspects of medical imaging science and positron emission tomography, particularly

  • nuclear imaging (PET and SPECT)

  • molecular imaging probe development

  • radiochemistry

  • use of radiometals

  • development of receptor protein targeting (small molecules, peptides and antibodies)

  • targeted radionuclides for therapy

  • radiopharmacy and translational research

Completed PhDs

  • Cheryll Allan (2005)

  • Christopher Fisher (2005)

  • Gary Nicholson (2006)

  • Jon Silversides (2006)

  • Amanda Sparke (2008)

  • Christopher Welch (2009) (2nd Supervisor)

  • Graeme McRobbie (2009)

  • Ryan Mewis (2009)

  • Abid Khan (2010)

  • Rachel Smith (2013)

  • Benjamin Burke (2013)

  • Naomi Jones (2015) (2nd Supervisor) 

  • Kati Nicholson (2015)

  • Ali Al-Zirgani (2016)

  • Neazar Baghdadi (2016)

  • Seraj Omar Al-Zahrani (2016)

  • Mustafa Al-Yassiry (2016)

  • Bassim Wahaab (2016)

  • David Millar (2016) (2nd supervisor)

  • Shubhanchi Nigam (2017)

  • Alicja Kownacka (2017)

Current PhD supervisions 

  • Zainab Abdallah Al-Ali

  • Boon-Uma Jowanarhidi

  • Hayley Bignell

  • Tahani Alresheedi

  • Fada Jabber

  • Rhiannon Lee

  • Isaline Renard

  • Rebecca Ullah (2nd supervisor)

  • James Thompson (2nd supervisor)

  • Noemi Perujo Holland (2nd supervisor)

 

Professional highlights

Academic qualifications

PhD Chemistry, University of Edinburgh (1995)

BSc Hons Chemistry, University of York (1992)

External roles

  • External examiner, MSc Radiopharmaceutics and PET Radiochemistry (King's College London)

  • External Examiner, MRes Bioimaging Sciences (Imperial College London)

  • External examiner of 30 PhD candidates at the universities of Oxford, Bath, Cardiff, Kent, Leeds, York, Edinburgh, Leicester, Birmingham, Manchester, Aberdeen, Imperial College, Newcastle, Warwick, King's College, Sydney (Australia), Reims (France), Denmark Technical (Denmark) and Burgundy (France)

  • Company Director, Daisy Medical Research Ltd

  • International grant review panel member; Academy of Finland, Chemistry and Radiochemistry Panel, Finland (2017) ANR Clio, France (2012) and ARP Physicancer France (2013-2015)

Awards and accolades

  • HEFCE Promising Researcher Fellowship (2005-2006)

  • Yorkshire Enterprise Fellowship (2009-10)

Professional highlights

  • Company Director, Daisy Medical Research Ltd, currently providing PET/CT scanning for circa 2,800 patients per annum at Castle Hill Hospital, Hull. (2013- )

  • Council member of Royal Society of Chemistry's Dalton Council (2010-2013)

  • UK representative for the British Council Pharmaceutics mission to India (2013)