Dr Matthew Hardman

Reader in Wound Healing / Director of Research

Faculty of Health Sciences

School of Life Sciences

m.hardman@hull.ac.uk

01482 461879

Dr Mat Hardman has more than 20 years' experience in the field of skin biology, with a specific focus on wound healing.

His research, which spans basic biology through to clinical studies, has been funded by the Medical Research Council, National Institutes of Health and a number of charities.

His wound healing group engage with a number of industry partners and the Hull and East Yorkshire Hospitals NHS Trust, ensuring a clear route to patient benefit.

Before moving to Hull, Mat was Director of the EPSRC & MRC Centre for Doctoral Training in Regeneration Medicine at the University of Manchester.

Research

Research Interests

  • Skin microbiota, host response and wound repair

  • Ageing, injury induced senescence and wound pathology

  • Hormonal modulation of skin repair

  • The role of hair follicles in wound repair

  • Macrophage polarisation and chronic wounds

  • Stress and wound healing, identifying and exploiting biological mediators

  • Novel therapies for promotion for wound healing

Research groups

Dr Mat Hardman is Academic Lead for the Advanced Wound Care Cluster at the University of Hull and Wound Healing Research Group Head for the Daisy Laboratories at Castle Hill Hospital.

Publications

Williams H, Crompton R A, Thomason H A, Campbell L, Singh G, McBain A J, Cruickshank S M, Hardman M J, 'Cutaneous Nod2 Expression Regulates the Skin Microbiome and Wound Healing in a Murine Model', Journal of Investigative Dermatology, epub: June 21, 2017.

Garcin C L, Huttner K M, Kirby N, Schneider P, Hardman M J, 'Ectodysplasin A Pathway Contributes to Human and Murine Wound Repair', Journal of Investigative Dermatology, 2016, 136:1022-30.

Garcin C L, Ansell D M, Headon D J, Paus R, Hardman M J, 'Hair Follicle Bulge Stem Cells Appear Dispensable for the Acute Phase of Wound Re-epithelialisation', Stem Cells, 2016, 34:1377-85.

Crompton R, Williams H, Cruickshank S, Hardman M J, 'Estrogen Promotes Healing in an LPS Bacterial Model of Delayed Cutaneous Wound Repair', Laboratory Investigation, 2016, 96;439-449.

Campbell L, Emmerson E, Davies F, Gilliver S C, Krust A, Chambon P, Ashcroft G S, Hardman M J, 'Estrogen Promotes Cutaneous Wound Healing via Estrogen Receptor Beta Independent of its Anti-Inflammatory Activities', Journal of Experimental Medicine, 2010, 207:1825-1833.

For a full list of Dr Hardman's publications, please follow this link.

Teaching

Programmes taught on

Modules list

  • Microbiology and Immunology

  • Molecular Genetics & Proteomics

  • Medical Microbiology

  • Research Projects

  • Reviews in Biology & Biomedical Sciences

  • Infection and Immunity

  • Biomedical Sciences Research Project

  • Research Project & Dissertation

  • Current Topics in Biomedical Science

Research PhDs

Dr Hardman welcomes applications in microbiology, cell biology, wound healing, stem cells, hair follicles and clinical studies.

Completed PhDs

David Ansell, Hair Cycle and Wound Healing.

Elaine Emmerson, Hormonal Modulation of Wound Healing.

Stuart Mills, Photodynamic Therapy for Wound Repair.

Laura Campbell, Immune-modulation of the Wound Response.

Nichola Cooper, PKCalpha and Cell Adhesion in Wound Healing.

Clare Garcin, EDAR Signaling and Hair Follicles in the Wound Response.

Matt Smith, Estrogen Receptor Polymorphisms in Wound Healing.

Chris Saville, Skin Ageing and Hormone Deficiency: Synergistic Interaction in Wound Healing.

Current PhD supervisions

Holly Wilkinson, The Role of Metals in Wound Healing, 2015-2019.

Sammi Iveson, Plasma for the Promotion of Wound Healing, 2017-2020.

Daniel Hardy, The Role of Hair Follicles in Wound Healing, 2017-2020.

Paul Weldrick, Novel Antimicrobials for Wound Healing, 2017-2020.

Professional highlights

Academic qualifications

  • BSc University of Manchester

  • PhD University of Manchester

External roles

  • Associate Editor, Experimental Dermatology

  • Large Grants Panel Member, British Skin Foundation

Awards and accolades

  • Research Into Ageing 30th Anniversary Research Fellowship

  • The Edmund de Rothschild Senior Fellowship in Ageing

  • Research Industry Collaborator of the Year (University of Manchester)